Hafnium Diselenide 2D Material-Based Surface Plasmon Resonance Sensor for Detection of Basal Cancer

IF 3.3 4区 物理与天体物理 Q2 CHEMISTRY, PHYSICAL Plasmonics Pub Date : 2024-09-11 DOI:10.1007/s11468-024-02518-8
Rajeev Kumar, Ritesh Singh Shah, Abdullah Saad Alsubaie, Naim Ben Ali, Mukesh Kumar, Amrindra Pal
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Abstract

Two-dimensional (2D) material-based surface plasmon resonance (SPR) sensor is proposed to detect the basal cancer at 633 nm wavelength. This work detects the analyte between refractive index (RI) 1.33 and 1.335 and also detects the particular application, such as normal and cancer basal cells (NBC and CBC), considered for analysis. This sensor consists of BK7 prism, gold (Au), and hafnium diselenide (HfSe2) materials which analyzed the performance parameters like sensitivity, full width at half maximum (FWHM), detection accuracy (DA), figure of merit (FoM), and penetration depth (PD). The sensitivity through the proposed sensor is maximum at a specific thickness of the Au layer. Calculated values of sensitivity for the proposed sensor are 275.47°/RIU with analyte RI of 1.33–1.335. Moreover, for basal cancer, the maximum sensitivity of 280.06°/RIU is achieved. The proposed sensor with high sensitivity is a suitable structure for the diagnosis of various cancer type applications.

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基于二维硒化铪材料的表面等离子体共振传感器用于检测基底癌
提出了基于二维(2D)材料的表面等离子体共振(SPR)传感器,用于检测波长为 633 nm 的基底癌。该作品可检测折射率 (RI) 在 1.33 和 1.335 之间的分析物,还可检测特定应用,如正常和癌症基底细胞(NBC 和 CBC)。该传感器由 BK7 棱镜、金(Au)和二硒化铪(HfSe2)材料组成,分析了灵敏度、半最大值全宽(FWHM)、检测精度(DA)、优点系数(FoM)和穿透深度(PD)等性能参数。在特定厚度的金层上,拟议传感器的灵敏度最大。拟议传感器的灵敏度计算值为 275.47°/RIU,分析物 RI 为 1.33-1.335。此外,对于基底癌,灵敏度最高可达 280.06°/RIU。所提出的传感器具有高灵敏度,是诊断各种癌症应用的合适结构。
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来源期刊
Plasmonics
Plasmonics 工程技术-材料科学:综合
CiteScore
5.90
自引率
6.70%
发文量
164
审稿时长
2.1 months
期刊介绍: Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.
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