High FOM Plasmonic Nanosensor for Blood Biomolecule Detection

IF 3.3 4区 物理与天体物理 Q2 CHEMISTRY, PHYSICAL Plasmonics Pub Date : 2024-08-22 DOI:10.1007/s11468-024-02487-y
Gaurav Kumar Yadav, Debanjan Sarkar, Sanjeev Kumar Metya
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Abstract

In this paper, a plasmonic refractive index sensor is proposed for label-free sensing of biomolecules present in blood. The sensor design is conceptualized on a metal-insulator-metal waveguide setup consisting of a microring and a plus-shaped enclosed within a U-shaped resonator separated by a linear rectangular bus waveguide. The transmittance characteristics of the proposed design are studied using the finite difference time domain methodology. The transmittance curve results in quintuple Fano resonances with sensitivities of 1152.6 nm/RIU (refractive index unit), 1116.6 nm/RIU, 1182.2 nm/RIU, 1438.6 nm/RIU and 2109.7 nm/RIU at resonant wavelengths of 1.055 \(\mu \)m, 1.146 \(\mu \)m, 1.223 \(\mu \)m, 1.494 \(\mu \)m, and 2.12 \(\mu \)m, respectively. Moreover, other performance parameters are also investigated including figure of merit, quality factor, and detection limit which comes out at a value of 91.3 \(RIU^{-1}\), 91.7, and 0.010, respectively. Furthermore, the sensor performance is investigated with respect to the detection of multiple biomolecules present in the blood. The highest sensitivity of 2180 nm/RIU is obtained with respect to analyte sensing.

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用于血液生物分子检测的高 FOM 质子纳米传感器
本文提出了一种质子折射率传感器,用于对血液中的生物分子进行无标记检测。传感器的设计构思是在金属-绝缘体-金属波导装置上实现的,该装置由一个微孔和一个加形波导组成,微孔和加形波导被封闭在一个 U 形谐振器内,谐振器之间用线性矩形母线波导隔开。利用有限差分时域方法研究了拟议设计的透射特性。透射率曲线产生了五倍法诺共振,灵敏度分别为 1152.6 nm/RIU(折射率单位)、1116.6 nm/RIU、1182.2 nm/RIU、1438.6 nm/RIU、2103.6 nm/RIU。6 nm/RIU 和 2109.7 nm/RIU,谐振波长分别为 1.055 (折射率)m、1.146 (折射率)m、1.223 (折射率)m、1.494 (折射率)m 和 2.12 (折射率)m。此外,还研究了其他性能参数,包括优点系数、品质因数和检测限,其值分别为 91.3 (RIU^{-1}\)、91.7 和 0.010。此外,还研究了传感器在检测血液中多种生物分子方面的性能。分析物传感的最高灵敏度为 2180 nm/RIU。
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来源期刊
Plasmonics
Plasmonics 工程技术-材料科学:综合
CiteScore
5.90
自引率
6.70%
发文量
164
审稿时长
2.1 months
期刊介绍: Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.
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