Clinical features and outcomes of retroperitoneal unicentric Castleman disease resected as sarcomas: insights from a high-volume sarcoma center

IF 1.6 4区医学 Q2 SURGERY Frontiers in Surgery Pub Date : 2024-09-05 DOI:10.3389/fsurg.2024.1371968

Haicheng Gao, Wenjie Li, Boyuan Zou, Shibo Liu, Chengli Miao

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Abstract

BackgroundCastleman disease (CD) is a rare lymphoproliferative disorder that can occur anywhere along the lymphatic pathway. Retroperitoneal unicentric Castleman disease (UCD) is an extremely rare manifestation. This study aims to explore the clinical features and surgical treatment of retroperitoneal UCD.MethodsWe retrospectively reviewed patients who underwent retroperitoneal tumor surgery and were diagnosed with CD based on postoperative pathology before December 31, 2022. Data from these patients were collected and analyzed.ResultsA total of 15 patients were included in the final analysis. All patients underwent radical resection under general anesthesia. Two out of 15 patients (13.3%) experienced serious complications but recovered well. There were no perioperative deaths. The median follow-up time was 78.5 months (range: 18–107.5 months), and no deaths or recurrences occurred during this period.ConclusionsSurgical treatment for retroperitoneal UCD is safe. Patients with retroperitoneal UCD can achieve long-time survival through complete resection.

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作为肉瘤切除的腹膜后单发卡斯特曼病的临床特征和预后：来自一个大容量肉瘤中心的启示

背景卡斯特曼病（CD）是一种罕见的淋巴组织增生性疾病，可发生在淋巴通路的任何部位。腹膜后单发卡斯特曼病（UCD）是一种极为罕见的表现。本研究旨在探讨腹膜后 UCD 的临床特征和手术治疗方法。方法我们回顾性研究了 2022 年 12 月 31 日之前接受腹膜后肿瘤手术并根据术后病理诊断为 CD 的患者。结果共有 15 例患者纳入最终分析。所有患者均在全身麻醉下接受了根治性切除术。15例患者中有2例（13.3%）出现严重并发症，但恢复良好。没有围手术期死亡病例。中位随访时间为 78.5 个月（18-107.5 个月），在此期间没有死亡或复发。结论腹膜后 UCD 的手术治疗是安全的，腹膜后 UCD 患者可以通过完全切除获得长期生存。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Surgery Medicine-Surgery

CiteScore

1.90

自引率

11.10%

发文量

1872

审稿时长

12 weeks

期刊介绍： Evidence of surgical interventions go back to prehistoric times. Since then, the field of surgery has developed into a complex array of specialties and procedures, particularly with the advent of microsurgery, lasers and minimally invasive techniques. The advanced skills now required from surgeons has led to ever increasing specialization, though these still share important fundamental principles. Frontiers in Surgery is the umbrella journal representing the publication interests of all surgical specialties. It is divided into several “Specialty Sections” listed below. All these sections have their own Specialty Chief Editor, Editorial Board and homepage, but all articles carry the citation Frontiers in Surgery. Frontiers in Surgery calls upon medical professionals and scientists from all surgical specialties to publish their experimental and clinical studies in this journal. By assembling all surgical specialties, which nonetheless retain their independence, under the common umbrella of Frontiers in Surgery, a powerful publication venue is created. Since there is often overlap and common ground between the different surgical specialties, assembly of all surgical disciplines into a single journal will foster a collaborative dialogue amongst the surgical community. This means that publications, which are also of interest to other surgical specialties, will reach a wider audience and have greater impact. The aim of this multidisciplinary journal is to create a discussion and knowledge platform of advances and research findings in surgical practice today to continuously improve clinical management of patients and foster innovation in this field.