Correction: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease

Abstract

Correction to: Cardiovasc Diabetol (2023) 22:217

https://doi.org/10.1186/s12933-023-01940-2

Following publication of the original article [1], the author noticed the errors in Fig. 2 and in Results section.

The bar graph is mistakenly duplicated in “percentage of plaque area of the aortic valves” of Fig. 2E. The corrected figure is given below:

Fig. 2

Acyl-GIP ameliorates dyslipidemia and atherosclerotic plaque formation in LDLR-/- male mice. Plasma (A) triglycerides, (B) cholesterol and (C) lipoprotein fractions as well as (D and E) the percentage of plaque area in aortic arches and valves and along the descending aorta of male LDLR-/- mice treated daily with either vehicle or acyl-GIP via subcutaneous injections for 28 days. n = 7. Blood lipids were determined from sac plasma at the end of the study. Data represent means ± SEM. *P < 0.05, **P < 0.01, *** P < 0.001, determined by unpaired two-sided t-test

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In Result section under the heading “GIPR-agonist acyl-GIP ameliorates dyslipidemia and atherosclerotic plaque formation in male LDLR-/- mice independently of weight loss”, the last sentence should read “Most importantly, acyl-GIP treatment was accompanied by reduced atherosclerotic plaque formation within the aortic valve and a trend to decrease fat streaks along the descending aorta (Fig. 2E)“ instead of “Most importantly, acyl-GIP treatment was accompanied by reduced atherosclerotic plaque formation within the aortic valve (Fig. 2G–H) and decreased fat streaks along the descending aorta (Fig. 2I)”.

1. Sachs S, Götz A, Finan B, et al. GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease. Cardiovasc Diabetol. 2023;22:217.https://doi.org/10.1186/s12933-023-01940-2

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Author notes

1. Stephan Sachs and Anna Götz contributed equally.

Authors and Affiliations

1. Institute for Diabetes and Regeneration, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764, Neuherberg, Germany

   Stephan Sachs, Anna Götz & Susanna M. Hofmann

2. Institute for Diabetes and Obesity, Division of Metabolic Diseases, Helmholtz Diabetes Center at Helmholtz Centre Munich, Munich, Germany

   Stephan Sachs, Anna Götz, Matthias H. Tschöp & Timo D. Müller

3. Technische Universität München, 80333, Munich, Germany

   Stephan Sachs & Matthias H. Tschöp

4. Novo Nordisk Research Center Indianapolis, Indianapolis, IN, USA

   Brian Finan

5. Research Unit Analytical Pathology, Helmholtz Center Munich, 85764, Neuherberg, Germany

   Annette Feuchtinger

6. Department of Chemistry, Indiana University, Bloomington, IN, USA

   Richard D. DiMarchi

7. Department of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

   Yvonne Döring

8. Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University Munich, Munich, Germany

   Yvonne Döring & Christian Weber

9. DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Munich, Germany

   Yvonne Döring & Christian Weber

10. Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands

    Christian Weber

11. Munich Cluster for Systems Neurology (SyNergy), Munich, Germany

    Christian Weber

12. German Center for Diabetes Research (DZD), 85764, Neuherberg, Germany

    Matthias H. Tschöp, Timo D. Müller & Susanna M. Hofmann

13. Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany

    Susanna M. Hofmann

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Corresponding authors

Correspondence to Timo D. Müller or Susanna M. Hofmann.

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Sachs, S., Götz, A., Finan, B. et al. Correction: GIP receptor agonism improves dyslipidemia and atherosclerosis independently of body weight loss in preclinical mouse model for cardio-metabolic disease. Cardiovasc Diabetol 23, 341 (2024). https://doi.org/10.1186/s12933-024-02407-8

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• Published: 12 September 2024

• DOI: https://doi.org/10.1186/s12933-024-02407-8

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