Microhemorrhages in diquat-induced encephalopathy identified using susceptibility-weighted imaging.

IF 3 3区 医学 Q2 TOXICOLOGY Clinical Toxicology Pub Date : 2024-09-12 DOI:10.1080/15563650.2024.2401073
Chuanying Shi,Weifei Wang
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Abstract

INTRODUCTION Intracerebral bleeding that predominantly affects the pons, midbrain, cerebral peduncle, basal ganglia, and thalamus may occur in severe diquat poisoning. We employed magnetic resonance-susceptibility-weighted imaging to highlight the presence of microhemorrhages in a patient with diquat poisoning.Case summary: A 15-year-old female patient presented with kidney and liver damage after ingesting diquat. Three days later, she developed coma. She received seven sessions of hemoperfusion and was discharged with residual cognitive impairment and right limb muscle weakness after 66 days of hospitalization.Images: Cranial computed tomography on day 5 and magnetic resonance imaging on day 8 revealed swelling in the pons, midbrain, and thalamus without evidence of hemorrhage. However, susceptibility-weighted imaging on day 8 demonstrated multiple punctate low signals, suggesting the presence of microhemorrhages. CONCLUSION Susceptibility-weighted imaging is a useful technique for detecting microhemorrhages in patients with diquat-induced encephalopathy, as microhemorrhages are often not detectable on computed tomography or conventional magnetic resonance imaging.
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利用易感加权成像技术识别敌草快诱发脑病的微出血点
导言:严重的敌草快中毒可能会出现主要影响脑桥、中脑、大脑脚、基底节和丘脑的脑出血。病例摘要:一名 15 岁的女性患者在摄入敌草快后出现肝肾损伤。三天后,她出现昏迷。她接受了 7 次血液灌流治疗,住院 66 天后,带着残留的认知障碍和右侧肢体肌无力出院:图像:第 5 天的头颅计算机断层扫描和第 8 天的磁共振成像显示,脑桥、中脑和丘脑肿胀,但无出血迹象。然而,第 8 天的感度加权成像显示出多个点状低信号,表明存在微出血。结论:感度加权成像是检测敌草快诱发脑病患者微出血的有效技术,因为计算机断层扫描或常规磁共振成像通常无法检测到微出血。
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来源期刊
Clinical Toxicology
Clinical Toxicology 医学-毒理学
CiteScore
5.70
自引率
12.10%
发文量
148
审稿时长
4-8 weeks
期刊介绍: clinical Toxicology publishes peer-reviewed scientific research and clinical advances in clinical toxicology. The journal reflects the professional concerns and best scientific judgment of its sponsors, the American Academy of Clinical Toxicology, the European Association of Poisons Centres and Clinical Toxicologists, the American Association of Poison Control Centers and the Asia Pacific Association of Medical Toxicology and, as such, is the leading international journal in the specialty.
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