{"title":"Enhanced Osteosarcoma Immunotherapy via CaCO3 Nanoparticles: Remodeling Tumor Acidic and Immune Microenvironment for Photodynamic Therapy (Adv. Healthcare Mater. 23/2024)","authors":"Yinghua Gao, Zhuoying Wang, Xinmeng Jin, Xiaoli Wang, Yining Tao, Shandeng Huang, Yun Wang, Yingqi Hua, Xuran Guo, Jing Xu, Zhengdong Cai","doi":"10.1002/adhm.202470147","DOIUrl":null,"url":null,"abstract":"<p><b>Osteosarcoma Photoimmunotherapy</b></p><p>In article 2400538, Yingqi Hua, Xuran Guo, Jing Xu, Zhengdong Cai, and co-workers design a new multicombination strategy that reprograms the immunosuppressive tumor microenvironment and enhances the effect of photodynamic therapy for osteosarcoma treatment. The combination of A-NPs@(SHK+Ce6) with programmed cell death protein 1 demonstrates remarkable ability in eliminating distant tumors and promoting long-term immune memory function, thereby protecting against tumor rechallenge.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":113,"journal":{"name":"Advanced Healthcare Materials","volume":null,"pages":null},"PeriodicalIF":10.0000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adhm.202470147","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Healthcare Materials","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/adhm.202470147","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Osteosarcoma Photoimmunotherapy
In article 2400538, Yingqi Hua, Xuran Guo, Jing Xu, Zhengdong Cai, and co-workers design a new multicombination strategy that reprograms the immunosuppressive tumor microenvironment and enhances the effect of photodynamic therapy for osteosarcoma treatment. The combination of A-NPs@(SHK+Ce6) with programmed cell death protein 1 demonstrates remarkable ability in eliminating distant tumors and promoting long-term immune memory function, thereby protecting against tumor rechallenge.
期刊介绍：
Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.
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