Drug Therapy Problems Identified by Clinical Pharmacists at a General Surgery Ward of an Academic Referral Hospital in Jordan

IF 2.8 3区医学 Q1 Pharmacology, Toxicology and Pharmaceutics Therapeutics and Clinical Risk Management Pub Date : 2024-09-11 DOI:10.2147/tcrm.s465128

Hiba Al Fahmawi, Abla Albsoul-Younes, Mohammad Saleh, Mahmoud Abu-Abeeleh, Violet Kasabri

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Abstract

Introduction: Drug therapy problems (DTPs) continuously occur in hospitalized patients. This study aims to emphasize the role of clinical pharmacists in evaluating the DTP’s frequencies, causes, severity ratings, and contributing factors at a general surgery ward in Jordan.
Methods: This prospective observational study was conducted at one of the major teaching and referral hospitals in Jordan. Data were collected through clinical pharmacist reviews of paper and electronic medical records as well as patient interviews. DTPs were identified using Cipolle’s classification system and rated for severity on a scale of 10. Multiple linear regression was performed to identify factors contributing to DTPs. Drug classes primarily associated with DTPs were specified.
Results: During enrollment, a total of 80 patients were recruited in this study. The mean age of the enrolled patients was 52.35 ± 14.82 years, and 49 (61.25%) of them were males. Within the study period, 192 DTPs were identified by clinical pharmacists in 87.5%of the total recruited patients. The mean number of DTPs per patient was 2.40 ± 1.83. The most common categories of DTPs were “needs additional therapy” 46 (23.96%), “unnecessary drug therapy” 45 (23.44%), and “dosage too low” 39 (20.31%). Of the total DTPs, 127 (66.15%) were rated as severe. Multiple linear regression revealed that patients’ length of hospital stay and the number of current medications had a statistically significant effect on the number of DTPs identified during hospitalization. Endocrine and metabolic drugs 51 (26.56%) and cardiovascular drugs 36 (18.75%) were the most frequent classes of drugs contributing to DTPs.
Conclusion: DTPs are common in the general surgery ward. Clinical pharmacists can provide medication reviews for surgical patients to identify DTPs and rate their severities. Detecting risk factors for DTPs and the most common drug classes associated with them can assist in decision-making relevant to reducing DTPs in the surgical ward.

Keywords: drug therapy problems, clinical pharmacist, surgery ward, observational study

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约旦一家学术转诊医院普通外科病房临床药剂师发现的药物治疗问题

简介住院病人不断出现药物治疗问题（DTP）。本研究旨在强调临床药剂师在评估约旦普外科病房 DTP 发生频率、原因、严重程度和诱因方面的作用：这项前瞻性观察研究在约旦一家主要的教学和转诊医院进行。数据通过临床药剂师对纸质和电子病历的审查以及对患者的访谈收集。使用西波尔分类系统识别 DTP，并将严重程度分为 10 级。为确定导致 DTP 的因素，进行了多元线性回归。结果：本研究共招募了 80 名患者。入组患者的平均年龄为（52.35 ± 14.82）岁，其中 49 人（61.25%）为男性。在研究期间，临床药剂师在所有招募患者中发现了 192 例 DTP，占总人数的 87.5%。每位患者的 DTP 平均数量为 2.40 ± 1.83。最常见的 DTP 类别为 "需要额外治疗 "46 例（23.96%）、"不必要的药物治疗 "45 例（23.44%）和 "剂量过低 "39 例（20.31%）。在所有 DTP 中，127 项（66.15%）被评为严重。多元线性回归显示，患者住院时间的长短和当前药物的数量对住院期间发现的 DTP 数量有显著的统计学影响。内分泌和代谢药物 51 种（26.56%）和心血管药物 36 种（18.75%）是导致 DTPs 的最常见药物类别：结论：DTPs 在普外科病房很常见。临床药剂师可为外科病人提供药物审查，以识别 DTPs 并评定其严重程度。发现 DTPs 的风险因素以及与之相关的最常见药物类别，有助于做出相关决策，减少外科病房的 DTPs。

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来源期刊

Therapeutics and Clinical Risk Management HEALTH CARE SCIENCES & SERVICES-

CiteScore

5.30

自引率

3.60%

发文量

139

审稿时长

16 weeks

期刊介绍： Therapeutics and Clinical Risk Management is an international, peer-reviewed journal of clinical therapeutics and risk management, focusing on concise rapid reporting of clinical studies in all therapeutic areas, outcomes, safety, and programs for the effective, safe, and sustained use of medicines, therapeutic and surgical interventions in all clinical areas. The journal welcomes submissions covering original research, clinical and epidemiological studies, reviews, guidelines, expert opinion and commentary. The journal will consider case reports but only if they make a valuable and original contribution to the literature. As of 18th March 2019, Therapeutics and Clinical Risk Management will no longer consider meta-analyses for publication. The journal does not accept study protocols, animal-based or cell line-based studies.