Renata Thomazini Dallago, Rafael Loch Batista, Berenice Bilharinho de Mendonça, Vania dos Santos Nunes Nogueira
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Abstract
Introduction Disorders of sex development (DSDs) were defined as congenital conditions in which the development of chromosomal, gonadal and anatomic sex is atypical. Nuclear receptor subfamily 5 group A member 1 (NR5A1), previously known as steroidogenic factor 1 (SF1) plays a crucial role in transcriptional regulation of genes involved in steroidogenesis, adrenal and gonadal development, and reproduction. NR5A1 emerged to be causative of 10 to 20% of 46,XY DSD.
IF 3.5 2区 医学Prevention SciencePub Date : 2021-10-01DOI: 10.1007/s11121-021-01230-x
Magreat Somba, Sylvia Kaaya, Hellen Siril, Kicki Oljemark, Donald Ainebyona, Elspeth McAdam, James Todd, Irene Andrew, Keith McAdam, Alice Simwinga, Neema Mleli, Samwel Makongwa, Sabina Haberlen, Mary C Smith Fawzi
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