{"title":"One Pot Synthesis of C3-Sulfurized Imidazolo [1,2-a] Pyridines","authors":"Ya-Dan Zhang, Zhi-Peng Guan, Zhi-Bing Dong","doi":"10.1021/acs.joc.4c01524","DOIUrl":null,"url":null,"abstract":"A facile and efficient annulation strategy was developed from easily accessible <i>a</i>-bromoketones, aminopyridines and benzazol, which afforded a series of imidazole [1,2-<i>a</i>]pyridine sulfides in moderate to good yields. The reaction involves the formation of C–N/C–S bond with the advantages of easy operation and wide substrates scope.","PeriodicalId":57,"journal":{"name":"The Journal of Organic Chemistry","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Organic Chemistry","FirstCategoryId":"1","ListUrlMain":"https://doi.org/10.1021/acs.joc.4c01524","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
A facile and efficient annulation strategy was developed from easily accessible a-bromoketones, aminopyridines and benzazol, which afforded a series of imidazole [1,2-a]pyridine sulfides in moderate to good yields. The reaction involves the formation of C–N/C–S bond with the advantages of easy operation and wide substrates scope.
期刊介绍:
The Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.