Identification of nontuberculous mycobacteria using the GenoType CMdirect and GenoType Mycobacterium CM line probe assays in GeneXpert MTB/RIF Ultra negative sputum: A South African prevalence study

IF 2.1 4区 医学 Q3 INFECTIOUS DISEASES Diagnostic microbiology and infectious disease Pub Date : 2024-09-10 DOI:10.1016/j.diagmicrobio.2024.116531
Christoffel Opperman , Chaldene Johannes , Sarishna Singh , Yonas Ghebrekristos , Rob Warren , Aliasgar Esmail , Wynand Goosen
{"title":"Identification of nontuberculous mycobacteria using the GenoType CMdirect and GenoType Mycobacterium CM line probe assays in GeneXpert MTB/RIF Ultra negative sputum: A South African prevalence study","authors":"Christoffel Opperman ,&nbsp;Chaldene Johannes ,&nbsp;Sarishna Singh ,&nbsp;Yonas Ghebrekristos ,&nbsp;Rob Warren ,&nbsp;Aliasgar Esmail ,&nbsp;Wynand Goosen","doi":"10.1016/j.diagmicrobio.2024.116531","DOIUrl":null,"url":null,"abstract":"<div><p>The GenoType CM<em>direct</em> Ver 1.0 and GenoType Mycobacterium Common Mycobacteria Ver 2.0-line probe assays were utilized to identify nontuberculous mycobacteria (NTM) from decontaminated sputum in a GeneXpert MTB/RIF Ultra negative cohort. A preliminary NTM prevalence of 1.7 % was observed, with a 100 % specificity. The high specificity advocates the CM<em>direct</em> as a possible rule-in test for NTM disease.</p></div>","PeriodicalId":11329,"journal":{"name":"Diagnostic microbiology and infectious disease","volume":"110 4","pages":"Article 116531"},"PeriodicalIF":2.1000,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic microbiology and infectious disease","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0732889324003560","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0

Abstract

The GenoType CMdirect Ver 1.0 and GenoType Mycobacterium Common Mycobacteria Ver 2.0-line probe assays were utilized to identify nontuberculous mycobacteria (NTM) from decontaminated sputum in a GeneXpert MTB/RIF Ultra negative cohort. A preliminary NTM prevalence of 1.7 % was observed, with a 100 % specificity. The high specificity advocates the CMdirect as a possible rule-in test for NTM disease.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
在 GeneXpert MTB/RIF 超阴性痰中使用 GenoType CMdirect 和 GenoType Mycobacterium CM 线探针检测法鉴定非结核分枝杆菌:南非流行病学研究
利用 GenoType CMdirect Ver 1.0 和 GenoType 分枝杆菌普通分枝杆菌 Ver 2.0 线探针检测法从 GeneXpert MTB/RIF Ultra 阴性队列中净化的痰液中鉴定非结核分枝杆菌(NTM)。初步观察到的非结核分枝杆菌感染率为 1.7%,特异性为 100%。CMdirect的高特异性证明它可以作为NTM疾病的常规检测方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
5.30
自引率
3.40%
发文量
149
审稿时长
56 days
期刊介绍: Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.
期刊最新文献
Isolation of nontuberculous mycobacteria and Nocardia via mycobacterial culture from pulmonary specimens COVID-19 study quantifying daily viral loads confirms throat samples are key to early diagnosis Prevalence, genotype distribution, and risk factors of Hepatitis E virus in blood donors, HIV patients, and pregnant women in Southwest Cameroon Modified time-to-positivity as a crucial determinant of short-term mortality among adults with community-onset monomicrobial bloodstream infections Analysis of respiratory RNA virus detection in the laboratory of a teaching hospital in Shanghai from 2017 to 2023
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1