Gentamicin and clindamycin antibiotic-eluting depot technology eradicates S. aureus in an implant-associated osteomyelitis pig model without systemic antibiotics
Nicole L. HenriksenElizabeth Serrano-ChávezAlbert Fuglsang-MadsenLouise K. JensenHans GottliebMats BueThomas L. AndresenJonas R. HenriksenAnders E. Hansen1Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark2Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark3Department of Orthopedic Surgery, Herlev Hospital, Herlev, Denmark4Department of Clinical Medicine, Aarhus University, Aarhus, Denmark5Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, DenmarkAnne-Catrin Uhlemann
{"title":"Gentamicin and clindamycin antibiotic-eluting depot technology eradicates S. aureus in an implant-associated osteomyelitis pig model without systemic antibiotics","authors":"Nicole L. HenriksenElizabeth Serrano-ChávezAlbert Fuglsang-MadsenLouise K. JensenHans GottliebMats BueThomas L. AndresenJonas R. HenriksenAnders E. Hansen1Department of Health Technology, Technical University of Denmark, Kgs. Lyngby, Denmark2Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark3Department of Orthopedic Surgery, Herlev Hospital, Herlev, Denmark4Department of Clinical Medicine, Aarhus University, Aarhus, Denmark5Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, DenmarkAnne-Catrin Uhlemann","doi":"10.1128/aac.00691-24","DOIUrl":null,"url":null,"abstract":"Antimicrobial Agents and Chemotherapy, Ahead of Print. <br/>","PeriodicalId":8152,"journal":{"name":"Antimicrobial Agents and Chemotherapy","volume":null,"pages":null},"PeriodicalIF":4.1000,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Antimicrobial Agents and Chemotherapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1128/aac.00691-24","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Antimicrobial Agents and Chemotherapy, Ahead of Print.
期刊介绍:
Antimicrobial Agents and Chemotherapy (AAC) features interdisciplinary studies that build our understanding of the underlying mechanisms and therapeutic applications of antimicrobial and antiparasitic agents and chemotherapy.