Novel humanized anti-PcrV monoclonal antibody COT-143 protects mice from lethal Pseudomonas aeruginosa infection via inhibition of toxin translocation by the type III secretion system
Shunsuke NumataTakafumi HaraMasaaki IzawaYosuke OkunoYasuhiko SatoShoji YamaneHideki MakiTakafumi SatoYoshinori Yamano1Laboratory for Drug Discovery and Disease Research, Shionogi & Co., Ltd., Toyonaka, Japan2Shionogi TechnoAdvance Research & Co., Ltd., Toyonaka, Japan3Business Development Department, Shionogi & Co., Ltd., Toyonaka, JapanJames E. Leggett
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引用次数: 0
Abstract
Antimicrobial Agents and Chemotherapy, Ahead of Print.
期刊介绍：
Antimicrobial Agents and Chemotherapy (AAC) features interdisciplinary studies that build our understanding of the underlying mechanisms and therapeutic applications of antimicrobial and antiparasitic agents and chemotherapy.
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