Fast GC–MS Method for Identification and Quantification of Terpenes from Cannabis Species

IF 1.2 4区 化学 Q4 BIOCHEMICAL RESEARCH METHODS Chromatographia Pub Date : 2024-09-17 DOI:10.1007/s10337-024-04364-6
Abdul Qudeer Ahmed, Rachel Yoonjo Park, David Noshad, Paul C. H. Li
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Abstract

We developed a rapid and user-friendly method to detect bioactive terpenes in different Cannabis flower samples based on gas chromatography-mass spectrometry (GC–MS). We validated the method in terms of linearity, repeatability, detection and quantitation limits and recovery. We quantitatively determine the amounts of six terpenes in seven Cannabis samples.

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用于鉴定和定量大麻品种中萜烯类化合物的快速气相色谱-质谱法
我们开发了一种基于气相色谱-质谱法(GC-MS)的快速、用户友好型方法,用于检测不同大麻花样品中的生物活性萜烯。我们从线性、重复性、检测和定量限以及回收率等方面对该方法进行了验证。我们定量测定了七种大麻样品中六种萜烯的含量。
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来源期刊
Chromatographia
Chromatographia 化学-分析化学
CiteScore
3.40
自引率
5.90%
发文量
103
审稿时长
2.2 months
期刊介绍: Separation sciences, in all their various forms such as chromatography, field-flow fractionation, and electrophoresis, provide some of the most powerful techniques in analytical chemistry and are applied within a number of important application areas, including archaeology, biotechnology, clinical, environmental, food, medical, petroleum, pharmaceutical, polymer and biopolymer research. Beyond serving analytical purposes, separation techniques are also used for preparative and process-scale applications. The scope and power of separation sciences is significantly extended by combination with spectroscopic detection methods (e.g., laser-based approaches, nuclear-magnetic resonance, Raman, chemiluminescence) and particularly, mass spectrometry, to create hyphenated techniques. In addition to exciting new developments in chromatography, such as ultra high-pressure systems, multidimensional separations, and high-temperature approaches, there have also been great advances in hybrid methods combining chromatography and electro-based separations, especially on the micro- and nanoscale. Integrated biological procedures (e.g., enzymatic, immunological, receptor-based assays) can also be part of the overall analytical process.
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