Analysis of the optical performance of intraocular lenses using profilometric measurements

Juan J. Miret, Vicente J. Camps, Celia García, Maria T. Caballero, Juan M. Gonzalez-Leal
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Abstract

Purpose

The aim of this study was to develop a methodology, based on profilometer measurements to assess the optical behaviour of Intraocular Lenses (IOls). The “Modulation Transfer Function through-object” (MTF through-object) based on vergence object displacement was calculated for different pupil sizes and pseudophakic eyes. Tilt and decentration were also analysed in a realistic cornea eye model.

Methods

For comparison between the different IOLs, an optical quality criterion based on a minimum value the MTF through-object and the recognition of simulated vision optotypes was introduced. Five IOLs were used in this study: Tecnis Eyhance, Mini Well, Tecnis Symfony, Tecnis Synergy and RayOne EMV.

Results

The technique was validated with previous methodologies. A general narrowing of the through-object MTF curve compared to the through-focus MTF curve was shown, resulting in greater distances between near and intermediate points and less depth of field around the far peak. The comparison between the IOLs showed that variations in corneal aberrations, pupil size and decentration caused relevant changes in IOL performance. A decrease of the SA produced a hypermetropic shift of the far focus between + 0.3 D and + 0.4 D. Most of IOLs worsen the optical quality as pupil size increased, even the MTF through-object shape changed. Decentration was an important factor in IOL implantation, causing a significant change in MTF through-object shape in most of IOLs.

Conclusions

This study highlights the need to evaluate pre-operative patients for corneal aberrations and pupillary size to have the best optical success after cataract surgery in multifocal or extended depth of focus IOLs.

Key messages

What is known

  • MTF(Modulation Transfer Function) through-focus curves (calculated in image space by moving the detector plane) can be obtained from optical bench assembly or from commercial devices.

  • Recently, some studies proposed to characterize the lens surface design based on the profilometric measurements

What is new

  • A novel methodology based on profilometer measurements to assess the optical behaviour of Intraocular Lenses (IOls) was shown.

  • The “Modulation Transfer Function through-object” based on vergence object displacement was introduced in order to analyse five premium IOLs.

  • MTF through-object curve is more appropriate for studying clinical behaviour, as it provides further near and intermediate points distances and lower depth of focus around far peak compare to MTF through-focus curves.

  • The optical behaviour of the five IOLs can vary considerably depending on the eye model and pupil size.

  • The effect of tilt and decentration on the MTF through-object the IOLs was analysed.

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利用轮廓测量法分析眼内透镜的光学性能
目的 本研究旨在开发一种基于轮廓仪测量的方法,用于评估眼内透镜(IOls)的光学性能。根据不同瞳孔大小和假性眼的瞳孔位移,计算出 "通过物体的调制传递函数"(MTF)。为了对不同的人工晶体进行比较,我们引入了一个光学质量标准,该标准基于通过物体的调制传递函数的最小值和模拟视力光型的识别。本研究使用了五种人工晶体:Tecnis Eyhance、Mini Well、Tecnis Symfony、Tecnis Synergy 和 RayOne EMV。与通过聚焦 MTF 曲线相比,通过物体 MTF 曲线普遍变窄,导致近点和中间点之间的距离变大,远峰周围的景深变小。人工晶体之间的比较表明,角膜像差、瞳孔大小和散焦的变化会导致人工晶体性能的相关变化。随着瞳孔的增大,大多数人工晶体的光学质量都会下降,甚至连通过物体的 MTF 形状都会发生变化。结论这项研究强调了对术前患者进行角膜像差和瞳孔大小评估的必要性,以便在白内障手术后使用多焦或延焦人工晶体获得最佳光学效果。最近,一些研究提出了基于轮廓仪测量来描述镜片表面设计的方法。与通过聚焦的 MTF 曲线相比,通过物体的 MTF 曲线能提供更远的近点和中点距离以及更低的远峰焦深,因此更适合研究临床表现。
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