Comparative Study for Safety and Efficacy of OAGB and SADJB-SG: A Retrospective Study

IF 2.8 3区医学 Q3 ENDOCRINOLOGY & METABOLISM Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Pub Date : 2024-09-19 DOI:10.2147/dmso.s484616

Mingyue Shang, Zhehong Li, Dexiao Du, Guangzhong Xu, Dongbo Lian, Zhaohui Liao, Dezhong Wang, Buhe Amin, Zheng Wang, Weijian Chen, Nengwei Zhang, Liang Wang

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Abstract

Purpose: Obesity and related complications are managed by One Anastomosis Gastric Bypass (OAGB) and Single Anastomosis Duodeno-Jejunal Bypass with Sleeve Gastrectomy (SADJB-SG), both of which are adapted from traditional gastric bypass procedures. However, there are no current comparative studies on the safety and efficacy of these two surgical procedures.
Patients and Methods: Preoperative baseline data of patients who had undergone OAGB and SADJB-SG surgeries from June 2019 to June 2021 were retrospectively analyzed at our bariatric facility. Postoperative data, including weight changes, improvement in type 2 diabetes (T2DM), and complication rates were collected over 2 years. This was followed by a comprehensive evaluation of the safety and efficacy of the two surgical procedures.
Results: A total of 63 patients completed the follow-up in this study. At the 24-month follow-up, excess weight loss percentage (EWL%) for the OAGB and SADJB-SG was 73.970± 5.005 and 75.652± 7.953, respectively (P-value = 0.310); total weight loss percentage (TWL%) was 24.006± 8.231 and 23.171± 6.600, respectively (P-value = 0.665). The diabetes remission rates for the two groups were 71.429% and 69.048%, respectively (P-value = 0.846). The cost for OAGB was 55088.208± 1508.220 yuan, which was significantly lower than the 57538.195± 1374.994 yuan for SADJB-SG (P-value< 0.001).
Conclusion: The two surgical procedures are reliable in terms of safety and efficacy, and each has distinct advantages. While OAGB has reduced operational expenses, SADJB-SG offers a broader range of applicability.

Keywords: one anastomosis gastric bypass, single anastomosis duodeno-jejunal bypass with sleeve gastrectomy, safety, efficacy

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OAGB 和 SADJB-SG 的安全性和有效性比较研究：一项回顾性研究

目的：单吻合胃旁路术（OAGB）和单吻合十二指肠空肠旁路术与袖状胃切除术（SADJB-SG）都是从传统胃旁路术改良而来，可治疗肥胖症及相关并发症。然而，目前还没有关于这两种手术的安全性和有效性的比较研究：我们对 2019 年 6 月至 2021 年 6 月期间在本院接受 OAGB 和 SADJB-SG 手术的患者的术前基线数据进行了回顾性分析。我们收集了两年内的术后数据，包括体重变化、2 型糖尿病（T2DM）改善情况和并发症发生率。随后对两种手术方法的安全性和有效性进行了综合评估：结果：共有 63 名患者完成了这项研究的随访。随访24个月时，OAGB和SADJB-SG的超重率（EWL%）分别为73.970± 5.005和75.652± 7.953（P值=0.310）；总减重率（TWL%）分别为24.006± 8.231和23.171± 6.600（P值=0.665）。两组的糖尿病缓解率分别为 71.429% 和 69.048%（P 值 = 0.846）。OAGB的费用为（55088.208±1508.220）元，明显低于SADJB-SG的（57538.195±1374.994）元（P值< 0.001）：两种手术方法在安全性和有效性方面都是可靠的，且各有优势。关键词：单吻合口胃旁路术；单吻合口十二指肠空肠旁路术联合袖状胃切除术；安全性；疗效

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来源期刊

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

5.90

自引率

6.10%

发文量

431

审稿时长

16 weeks

期刊介绍： An international, peer-reviewed, open access, online journal. The journal is committed to the rapid publication of the latest laboratory and clinical findings in the fields of diabetes, metabolic syndrome and obesity research. Original research, review, case reports, hypothesis formation, expert opinion and commentaries are all considered for publication.