Effects of Health Technology Use and Digital Health Engagement on Clinical Trial Participation: Findings from the Health Information National Trends Survey

Nicholas C Peiper, Stephen Furmanek, Kelly C McCants, Edward Hoyt Brown
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Abstract

Background: Clinical trials are critical to scientific advances and medical progress, although awareness and participation remain low in general populations. The existing literature indicates that clinical trial knowledge and participation is multifactorial. Yet, little is known about the association between clinical trial participation with health technology use and digital health engagement to search for health information, interact with medical providers, and seek health supports. Objective: Examine the multivariate association between clinical trial knowledge and participation with past-year health technology use and digital health engagement with medical providers. Design: Cross-sectional data from a federal surveillance system. Participants: A total of 3,865 US adult respondents from the Health Information National Trends Survey 5, Cycle 4 conducted in 2020. Main Measures: The two outcomes were clinical trial knowledge (no knowledge, a little knowledge, a lot of knowledge) and participation (never invited, invited did not participate, invited and participated). There were four binary indicators of health technology use for the following purposes in the past year: searching for health or medical information, communicating with a doctors office, looking up medical test results, and making medical appointments. There were four binary indicators of digital health engagement in the past year: sharing health information on social media, participating in a health forum or support group, watching health-related videos on YouTube, and awareness of ClinicalTrials.gov. Key Results: Survey-weighted multivariate regression models demonstrated that awareness of ClinicalTrials.gov had the largest associations with clinical trial knowledge and participation. Digital technology use to engage with medical providers and electronic health records was associated with clinical participation, although the vast majority of respondents had never been invited. Conclusions: Findings from this study can inform the design of large-scale digital health campaigns and quality improvement programs focused on increasing clinical trial participation.
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医疗技术使用和数字医疗参与对临床试验参与的影响:全国健康信息趋势调查的结果
背景:临床试验对科学进步和医学发展至关重要,但普通人群对临床试验的认知度和参与度仍然很低。现有文献表明,临床试验知识和参与是多因素的。然而,人们对临床试验的参与与健康技术的使用以及搜索健康信息、与医疗服务提供者互动和寻求健康支持的数字健康参与之间的关系知之甚少。研究目的研究临床试验知识和参与度与过去一年健康技术使用情况以及与医疗服务提供者的数字健康互动之间的多变量关联。设计:来自联邦监测系统的横断面数据。参试者2020年进行的第五次全国健康信息趋势调查(Health Information National Trends Survey 5)第4周期的3865名美国成人受访者。主要测量指标:两个结果是临床试验知识(不了解、略有了解、非常了解)和参与情况(从未受邀、受邀未参与、受邀并参与)。在过去一年中,健康技术的使用有四个二进制指标:搜索健康或医疗信息、与医生办公室沟通、查询医疗检查结果和预约就诊。在过去一年中,数字健康参与度有四个二进制指标:在社交媒体上分享健康信息、参加健康论坛或支持小组、在 YouTube 上观看健康相关视频以及了解 ClinicalTrials.gov。主要结果调查加权多元回归模型表明,ClinicalTrials.gov 的认知度与临床试验知识和参与度的关联度最大。使用数字技术与医疗服务提供者和电子健康记录互动与临床参与相关,尽管绝大多数受访者从未收到过邀请。结论:这项研究的结果可为设计大规模数字健康活动和质量改进计划提供参考,这些活动和计划的重点是提高临床试验的参与率。
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