Factors affecting discrepancies in disease activity evaluation between patients and physicians in systemic lupus erythematosus-The importance of symptoms such as fatigue

IF 1.9 4区 医学 Q3 RHEUMATOLOGY Lupus Pub Date : 2024-09-14 DOI:10.1177/09612033241281909
Hiroshi Doi, Koichiro Ohmura, Motomu Hashimoto, Kentaro Ueno, Yudai Takase, Ryuta Inaba, Tomohiro Kozuki, Takeshi Iwasaki, Masashi Taniguchi, Yuya Tabuchi, Mirei Shirakashi, Hideo Onizawa, Hideaki Tsuji, Akira Onishi, Ryu Watanabe, Koji Kitagori, Shuji Akizuki, Kosaku Murakami, Ran Nakashima, Hajime Yoshifuji, Wataru Yamamoto, Takahiro Itaya, Ryuji Uozumi, Masao Tanaka, Akio Morinobu
{"title":"Factors affecting discrepancies in disease activity evaluation between patients and physicians in systemic lupus erythematosus-The importance of symptoms such as fatigue","authors":"Hiroshi Doi, Koichiro Ohmura, Motomu Hashimoto, Kentaro Ueno, Yudai Takase, Ryuta Inaba, Tomohiro Kozuki, Takeshi Iwasaki, Masashi Taniguchi, Yuya Tabuchi, Mirei Shirakashi, Hideo Onizawa, Hideaki Tsuji, Akira Onishi, Ryu Watanabe, Koji Kitagori, Shuji Akizuki, Kosaku Murakami, Ran Nakashima, Hajime Yoshifuji, Wataru Yamamoto, Takahiro Itaya, Ryuji Uozumi, Masao Tanaka, Akio Morinobu","doi":"10.1177/09612033241281909","DOIUrl":null,"url":null,"abstract":"ObjectivesThere are often discrepancies in the evaluation of disease activity between patients and physicians in systemic lupus erythematosus (SLE). In this study, we examined the factors that affect those evaluations.MethodsPhysician visual analogue scale (Ph-VAS), patient VAS (Pt-VAS), Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2k), glucocorticoid (GC) usage and dose, age, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index, and three patient-reported outcomes (SLE symptom checklist [SSC], short-form 36 questionnaire [SF-36], and LupusPRO) were obtained from a study performed in 2019 using 225 SLE outpatients of the Kyoto Lupus Cohort at Kyoto University Hospital. Correlations among Ph-VAS, Pt-VAS, or dif (Pt-VAS-Ph-VAS) (Pt-VAS minus Ph-VAS) and other factors were examined.ResultsWe found a significant discrepancy between Pt-VAS (median 38.0 mm) and Ph-VAS (median 18.7 mm) scores ( p < 0.001). SSC score showed a significant correlation with Pt-VAS and dif (Pt-VAS-Ph-VAS) ( p < 0.001). Among SSC items, fatigue showed the most significant correlation with dif (Pt-VAS-Ph-VAS). We also showed that higher dif (Pt-VAS-Ph-VAS) was associated with lower quality of life (QOL) evaluated by SF-36 and LupusPRO.ConclusionsPt-VAS scores tended to be higher than Ph-VAS scores, and the discrepancy was influenced mainly by fatigue. Higher dif (Pt-VAS-Ph-VAS) was associated with lower patient QOL.","PeriodicalId":18044,"journal":{"name":"Lupus","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lupus","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/09612033241281909","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RHEUMATOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

ObjectivesThere are often discrepancies in the evaluation of disease activity between patients and physicians in systemic lupus erythematosus (SLE). In this study, we examined the factors that affect those evaluations.MethodsPhysician visual analogue scale (Ph-VAS), patient VAS (Pt-VAS), Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2k), glucocorticoid (GC) usage and dose, age, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index, and three patient-reported outcomes (SLE symptom checklist [SSC], short-form 36 questionnaire [SF-36], and LupusPRO) were obtained from a study performed in 2019 using 225 SLE outpatients of the Kyoto Lupus Cohort at Kyoto University Hospital. Correlations among Ph-VAS, Pt-VAS, or dif (Pt-VAS-Ph-VAS) (Pt-VAS minus Ph-VAS) and other factors were examined.ResultsWe found a significant discrepancy between Pt-VAS (median 38.0 mm) and Ph-VAS (median 18.7 mm) scores ( p < 0.001). SSC score showed a significant correlation with Pt-VAS and dif (Pt-VAS-Ph-VAS) ( p < 0.001). Among SSC items, fatigue showed the most significant correlation with dif (Pt-VAS-Ph-VAS). We also showed that higher dif (Pt-VAS-Ph-VAS) was associated with lower quality of life (QOL) evaluated by SF-36 and LupusPRO.ConclusionsPt-VAS scores tended to be higher than Ph-VAS scores, and the discrepancy was influenced mainly by fatigue. Higher dif (Pt-VAS-Ph-VAS) was associated with lower patient QOL.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
影响系统性红斑狼疮患者与医生之间疾病活动性评估差异的因素--疲劳等症状的重要性
目的系统性红斑狼疮(SLE)患者和医生对疾病活动性的评估往往存在差异。本研究探讨了影响这些评估的因素。方法医师视觉模拟量表(Ph-VAS)、患者VAS(Pt-VAS)、2000年系统性红斑狼疮疾病活动指数(SLEDAI-2k)、糖皮质激素(GC)的使用情况和剂量、年龄、系统性红斑狼疮国际合作诊所/美国风湿病学会损害指数、患者报告的三种结果(系统性红斑狼疮症状核对表[SSC]、SF-36短式问卷[SF-36]和LupusPRO)来自于2019年进行的一项研究,该研究使用了京都大学医院京都狼疮队列的225名系统性红斑狼疮门诊患者。结果我们发现Pt-VAS(中位数38.0毫米)和Ph-VAS(中位数18.7毫米)得分之间存在显著差异(p <0.001)。SSC 评分与 Pt-VAS 和 dif(Pt-VAS-Ph-VAS)呈显著相关(p < 0.001)。在 SSC 项目中,疲劳与 dif(Pt-VAS-Ph-VAS)的相关性最大。我们还发现,较高的dif(Pt-VAS-Ph-VAS)与SF-36和LupusPRO评估的较低生活质量(QOL)相关。差异越大(Pt-VAS-Ph-VAS),患者的生活质量越低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Lupus
Lupus 医学-风湿病学
CiteScore
4.20
自引率
11.50%
发文量
225
审稿时长
1 months
期刊介绍: The only fully peer reviewed international journal devoted exclusively to lupus (and related disease) research. Lupus includes the most promising new clinical and laboratory-based studies from leading specialists in all lupus-related disciplines. Invaluable reading, with extended coverage, lupus-related disciplines include: Rheumatology, Dermatology, Immunology, Obstetrics, Psychiatry and Cardiovascular Research…
期刊最新文献
Health seeking behaviour and diagnostic delays in SLE: A multi-ethnic Malaysian cohort study. Rituximab in lupus anticoagulant hypoprothrombinemia syndrome: A case report. Different patterns of longitudinal changes in antinuclear antibodies titers in children with systemic lupus erythematosus and Sjögren's syndrome. Optical coherence tomography angiography findings of systemic lupus erythematosus patients and the effect of neuropsychiatric involvement on it. Correlation between ABO blood group and clinical characteristics of patients with lupus nephritis.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1