{"title":"Chemical composition and antibacterial activity of the essential oil of Coreopsis lanceolata leaves","authors":"Antônio, Crotti, Richard, Lima, Ana Carla, Colli, Sara, Souza, Milton, Groppo, Carlos, Martins","doi":"10.26434/chemrxiv-2024-dk7v6","DOIUrl":null,"url":null,"abstract":"We have evaluated the antibacterial activity of the essential oil of the leaves of Coreopsis lanceolata (CL-EO) collected in southeastern Brazil. against a representative panel of cariogenic bacteria. The activity was evaluated in terms of its Minimum Inhibitory Concentration (MIC) values. CL-EO displays moderate activity against Streptococcus mutans, S. sanguinis, S. salivarus, S. sobrinus, Lactobacillus paracasei, and Enterococcus faecalis (MIC = 1000 µg/mL) and strong activity against S. mitis (MIC = 500 µg/mL). We have identified 1,11-tridecadiene-3,5,7,9-tetrayne (48.9%), β-bisabolene (22.8%), germacrene D (9.2%), and globulol (4.6%) as the major compounds in CL-EO. This is the first report on the chemical composition of the essential oil obtained from C. lanceolata leaves.","PeriodicalId":9813,"journal":{"name":"ChemRxiv","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ChemRxiv","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26434/chemrxiv-2024-dk7v6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We have evaluated the antibacterial activity of the essential oil of the leaves of Coreopsis lanceolata (CL-EO) collected in southeastern Brazil. against a representative panel of cariogenic bacteria. The activity was evaluated in terms of its Minimum Inhibitory Concentration (MIC) values. CL-EO displays moderate activity against Streptococcus mutans, S. sanguinis, S. salivarus, S. sobrinus, Lactobacillus paracasei, and Enterococcus faecalis (MIC = 1000 µg/mL) and strong activity against S. mitis (MIC = 500 µg/mL). We have identified 1,11-tridecadiene-3,5,7,9-tetrayne (48.9%), β-bisabolene (22.8%), germacrene D (9.2%), and globulol (4.6%) as the major compounds in CL-EO. This is the first report on the chemical composition of the essential oil obtained from C. lanceolata leaves.
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