{"title":"Incorrigible inflammation","authors":"Hany Ariffin","doi":"10.1111/bjh.19773","DOIUrl":null,"url":null,"abstract":"Haemophagocytic lymphohistiocytosis (HLH) that occurs concomitantly with leukaemia can be initially missed due to overlapping clinical features. In a series of three cases, Tanabe and colleagues illustrate the need for prompt recognition of HLH and institution of HLH‐directed therapy to prevent hyperinflammation‐mediated multi‐organ damage and death.Commentary on: Tanabe et al. Paediatric acute lymphoblastic leukaemia‐associated haemophagocytic lymphohistiocytosis develops during prednisolone prephase. Br J Haematol 2024 (Online ahead of print). doi: <jats:ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"https://doi.org/10.1111/bjh.19755\">10.1111/bjh.19755</jats:ext-link>.","PeriodicalId":135,"journal":{"name":"British Journal of Haematology","volume":null,"pages":null},"PeriodicalIF":5.1000,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"British Journal of Haematology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/bjh.19773","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"HEMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Haemophagocytic lymphohistiocytosis (HLH) that occurs concomitantly with leukaemia can be initially missed due to overlapping clinical features. In a series of three cases, Tanabe and colleagues illustrate the need for prompt recognition of HLH and institution of HLH‐directed therapy to prevent hyperinflammation‐mediated multi‐organ damage and death.Commentary on: Tanabe et al. Paediatric acute lymphoblastic leukaemia‐associated haemophagocytic lymphohistiocytosis develops during prednisolone prephase. Br J Haematol 2024 (Online ahead of print). doi: 10.1111/bjh.19755.
期刊介绍:
The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.