Semantic search using protein large language models detects class II microcins in bacterial genomes

IF 5 2区生物学 Q1 MICROBIOLOGY mSystems Pub Date : 2024-09-18 DOI:10.1128/msystems.01044-24

Anastasiya V. KulikovaJennifer K. ParkerBryan W. DaviesClaus O. Wilke1Department of Integrative Biology, The University of Texas at Austin, Austin, Texas, USA2Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas, USA3John Ring LaMontagne Center for Infectious Diseases, The University of Texas at Austin, Austin, Texas, USAMarnix Medema

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Abstract

mSystems, Ahead of Print.

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利用蛋白质大语言模型进行语义搜索，检测细菌基因组中的第二类微球蛋白

mSystems, Ahead of Print.

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来源期刊

mSystems Biochemistry, Genetics and Molecular Biology-Biochemistry

CiteScore

10.50

自引率

3.10%

发文量

308

审稿时长

13 weeks

期刊介绍： mSystems™ will publish preeminent work that stems from applying technologies for high-throughput analyses to achieve insights into the metabolic and regulatory systems at the scale of both the single cell and microbial communities. The scope of mSystems™ encompasses all important biological and biochemical findings drawn from analyses of large data sets, as well as new computational approaches for deriving these insights. mSystems™ will welcome submissions from researchers who focus on the microbiome, genomics, metagenomics, transcriptomics, metabolomics, proteomics, glycomics, bioinformatics, and computational microbiology. mSystems™ will provide streamlined decisions, while carrying on ASM''s tradition of rigorous peer review.