XU-NetI: Simple U-shaped encoder-decoder network for accurate imputation of multivariate missing data

Firdaus Firdaus , Siti Nurmaini , Bambang Tutuko , Muhammad Naufal Rachmatullah , Anggun Islami , Annisa Darmawahyuni , Ade Iriani Sapitri , Widya Rohadatul Ais'sy , Muhammad Irfan Karim , Muhammad Fachrurrozi , Ahmad Zarkasi
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Abstract

Patients in intensive care unit (ICU) often have multiple vital signs monitored continuously. However, missing data is common in ICU settings, negatively impacting clinical decision-making and patient outcomes. In this study propose a multivariate data imputation method based on simple U-Shaped encoder-decoder network imputation (XU-NetI) method to learn the underlying patterns in the data and generate imputations for missing values of vital signs data with ICU patients. To evaluate the performance of this study's imputation methods, this study employed a publicly available database such the medical information mart for intensive care III (MIMIC III) v1.4. In this study proposed model has been developed to analyze 219.281 vital sign worth of data, focusing on eight essential vital sign features: body temperature, heart rate, respiration rate, systolic blood pressure, diastolic blood pressure, mean blood pressure, oxygen saturation, and glucose. The evaluation results demonstrates the effectiveness of the imputation techniques in improving the accuracy of predictive models. This study compared the XU-NetI approach to other state-of-the-art imputation methods including Autoencoder and Convolutional Neural Networks. As a result found, the technique using XU-NetI architecture outperformed them, in terms of root mean square error (RSME) by approximately 0.01, mean absolute error (MAE) by approximately 0.009, and R square (R2) by approximately 0.99. The XU-NetI method has the potential to enhance clinical decision-making and improve patient outcomes.

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XU-NetI:用于准确估算多元缺失数据的简单 U 型编码器-解码器网络
重症监护室(ICU)的患者通常需要持续监测多种生命体征。然而,数据缺失在 ICU 环境中很常见,对临床决策和患者预后产生了负面影响。本研究提出了一种基于简单 U 型编码器-解码器网络估算(XU-NetI)方法的多变量数据估算方法,以学习数据中的潜在模式,并生成 ICU 患者生命体征数据缺失值的估算值。为了评估本研究的估算方法的性能,本研究使用了一个公开的数据库,如重症监护医疗信息集市 III(MIMIC III)V1.4。本研究提出的模型可分析价值 219.281 个生命体征的数据,重点关注八个基本生命体征特征:体温、心率、呼吸频率、收缩压、舒张压、平均血压、血氧饱和度和血糖。评估结果表明了估算技术在提高预测模型准确性方面的有效性。这项研究将 XU-NetI 方法与其他最先进的估算方法(包括自动编码器和卷积神经网络)进行了比较。结果发现,使用 XU-NetI 架构的技术在均方根误差 (RSME) 约 0.01、平均绝对误差 (MAE) 约 0.009 和 R 平方 (R2) 约 0.99 方面均优于它们。XU-NetI方法具有增强临床决策和改善患者预后的潜力。
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