Brown adipose tissue fights the battle against leukaemia

IF 31 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM Nature Reviews Endocrinology Pub Date : 2024-09-20 DOI:10.1038/s41574-024-01043-2
Pamela Fischer-Posovszky, Julia Zinngrebe
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Abstract

Brown adipocytes are increasingly recognized as a promising therapeutic target for metabolic disorders. Research published in Advanced Science now presents evidence that these cells might also be useful for leukaemia therapy. The study demonstrates that activation of brown adipocytes deprives leukaemia cells of glucose, which reveals a potential new avenue for leukaemia treatment.

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棕色脂肪组织对抗白血病
棕色脂肪细胞被越来越多的人认为是治疗代谢性疾病的理想靶点。发表在《先进科学》(Advanced Science)上的研究现在提供了证据,证明这些细胞也可用于白血病治疗。研究表明,激活棕色脂肪细胞可使白血病细胞无法获得葡萄糖,这为白血病治疗提供了一条潜在的新途径。
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来源期刊
Nature Reviews Endocrinology
Nature Reviews Endocrinology 医学-内分泌学与代谢
CiteScore
42.00
自引率
0.70%
发文量
158
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Endocrinology aspires to be the foremost platform for reviews and commentaries catering to the scientific communities it serves. The journal aims to publish articles characterized by authority, accessibility, and clarity, enhanced with easily understandable figures, tables, and other visual aids. The goal is to offer an unparalleled service to authors, referees, and readers, striving to maximize the usefulness and impact of each article. Nature Reviews Endocrinology publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians in the fields of endocrinology and metabolism. Its broad scope ensures that the work it publishes reaches the widest possible audience.
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