Biprajit Paul , Sayak Ghosh , Surajit Das , Indranil Chatterjee
{"title":"Fe(iii)-catalyzed p-selective C–H bond chalcogenation of phenols†","authors":"Biprajit Paul , Sayak Ghosh , Surajit Das , Indranil Chatterjee","doi":"10.1039/d4ob01382d","DOIUrl":null,"url":null,"abstract":"<div><div>An efficient, eco-friendly, and scalable protocol has been introduced for the <em>p</em>-selective C–X (X = Se/S) bond formation of phenols employing earth-abundant, less-toxic Fe(<span>iii</span>)-catalysts and the green solvent ethanol without using any directing template, stabilizing ligands, oxidants, or additives. The key attraction lies in the impressive <em>p</em>-selectivity with moderate to good yields, wide functional group compatibility under mild aerobic reaction conditions, and the synthetic modification of the products towards value-added molecules.</div></div>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":"22 40","pages":"Pages 8133-8137"},"PeriodicalIF":2.7000,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic & Biomolecular Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1477052024008152","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/9 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
An efficient, eco-friendly, and scalable protocol has been introduced for the p-selective C–X (X = Se/S) bond formation of phenols employing earth-abundant, less-toxic Fe(iii)-catalysts and the green solvent ethanol without using any directing template, stabilizing ligands, oxidants, or additives. The key attraction lies in the impressive p-selectivity with moderate to good yields, wide functional group compatibility under mild aerobic reaction conditions, and the synthetic modification of the products towards value-added molecules.
期刊介绍:
Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.