{"title":"Synthesis of unsymmetrical 2,4-diaryl substituted and 3-bromo-2-(4-bromoalkoxy)-derived pyranocoumarins.","authors":"Velu Saravanan, Pin-Hui Lin, Ding-Yah Yang","doi":"10.1039/d4ob01353k","DOIUrl":null,"url":null,"abstract":"<p><p>A series of unsymmetrical 2,4-disubstituted pyranocoumarins and 3-bromo-2-(4-bromoalkoxy)-derived pyranocoumarins were synthesized <i>via</i> the palladium-catalyzed C-H arylation of 4-phenyl-4<i>H</i>,5<i>H</i>-pyrano[3,2-<i>c</i>]chromen-5-ones with aryl iodide and the three-component reaction of 4-phenyl-4<i>H</i>,5<i>H</i>-pyrano[3,2-<i>c</i>]chromen-5-one with bromine and cyclic ether, respectively.</p>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic & Biomolecular Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d4ob01353k","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
A series of unsymmetrical 2,4-disubstituted pyranocoumarins and 3-bromo-2-(4-bromoalkoxy)-derived pyranocoumarins were synthesized via the palladium-catalyzed C-H arylation of 4-phenyl-4H,5H-pyrano[3,2-c]chromen-5-ones with aryl iodide and the three-component reaction of 4-phenyl-4H,5H-pyrano[3,2-c]chromen-5-one with bromine and cyclic ether, respectively.