Outcomes of Prophylactic Inguinal Lymph Node Dissection in Malignancies of Lower Limb.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL Annals of African Medicine Pub Date : 2024-10-01 Epub Date: 2024-09-14 DOI:10.4103/aam.aam_164_22
Prabhat Bhaskarrao Nichkaode, Bijay Sharma, Sreemanth Reddy, Ramteja Inturi, Aditya Patil
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Abstract

Aim: To evaluate the role of early prophylactic inguinal node dissection in patients with squamous cell cancer and melanoma of lower limb.

Materials and methods: From 2008 to 2018, a Tertiary Care Hospital connected to a teaching institute served as the site of this retrospective observational study. Patient records were gathered with the purpose of gathering clinical, investigative, surgical, pathological and follow-up information.

Results: We included 33 patients in this analysis out of the 47 patients we treated ourselves between 2008 and 2018; among these 33 patients, 21 (63.63%) had palpable inguinal nodes at the time of primary presentation. All 21 patients' FNAC tests were positive for metastases, in 16 patients (76.19%). 5 patients on FNAC (23.80%) exhibited not metastases. The remaining 12 patients did not have enlarged lymph nodes at the time of their initial presentation. Patients who did not have palpable lymph node were given the option of having a modified inguinal block dissection. 8 patients with metastatic disease have nodes that are positive in histology. In addition, out of 5 patients with negative nodes 4 (80%) showed evidence of metastasis.

Conclusion: The conclusion of this retrospective observational study is that although palpable lymph nodes in groin are unquestionably a sign that inguinal nodes should be dissected, prophylactic lymph node dissection should be still done even if nodes are not palpable or provide a negative FNAC result. Given that delayed lymphadenectomy has a significant effect on survival, delaying inguinal lymphadenectomy in non-palpable nodes could cause you to lose the battle against cancer in your lower limb. The related surgical morbidity is the only downside to prophylactic lymph node dissection. This can, however, be effectively decreased with a modified inguinal lymphadenectomy operation.

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下肢恶性肿瘤预防性腹股沟淋巴结清扫术的效果
目的:评估早期预防性腹股沟结节切除术在下肢鳞癌和黑色素瘤患者中的作用:2008 年至 2018 年,一家与教学机构相连的三级甲等医院作为本回顾性观察研究的研究地点。我们收集了患者的病历,目的是收集临床、检查、手术、病理和随访信息:在2008年至2018年期间,我们对47名患者进行了治疗,其中33名患者在初诊时可触及腹股沟结节,在这33名患者中,有21名患者(63.63%)在初诊时可触及腹股沟结节。所有 21 名患者的 FNAC 检查均为转移阳性,其中 16 名患者(76.19%)。5 名患者(23.80%)的 FNAC 检查结果显示没有转移。其余 12 名患者在初次发病时淋巴结没有肿大。未触及淋巴结的患者可选择进行改良腹股沟区块清扫术。8 名转移性疾病患者的淋巴结在组织学上呈阳性。此外,在 5 名淋巴结阴性的患者中,有 4 人(80%)有转移证据:这项回顾性观察研究得出的结论是,尽管腹股沟可触及淋巴结无疑是应切除腹股沟淋巴结的信号,但即使无法触及淋巴结或 FNAC 结果为阴性,仍应进行预防性淋巴结切除。鉴于延迟淋巴结切除对患者的生存有很大影响,因此,延迟对无法触及的结节进行腹股沟淋巴结切除可能会导致患者输掉与下肢癌症的斗争。相关的手术发病率是预防性淋巴结清扫的唯一缺点。不过,通过改良的腹股沟淋巴结切除手术,可以有效降低发病率。
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来源期刊
Annals of African Medicine
Annals of African Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
31
期刊介绍: The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.
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