Review on novel pharmaceutical applications of hupu gum: A versatile natural polymer.

IF 1 Q4 PHARMACOLOGY & PHARMACY Annales pharmaceutiques francaises Pub Date : 2024-09-19 DOI:10.1016/j.pharma.2024.09.008
Rajeswari Aleti, Monika Nijhawan, Pavan Kumar Thota, Bhavana Jidige
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Abstract

The pharmaceutical research on natural excipients with diverse physicochemical properties useful in various novel drug delivery systems is a growing interest. The market for natural gums like hupu gum (gum kondagogu) is growing globally, driven by increasing consumer preference for natural and sustainable ingredients. This review covers botanical origin, geographical distribution, chemical constituents, identification tests, toxicology studies and potential applications of hupu gum in novel drug delivery systems. Emphasis is placed on its traditional uses in indigenous medicine and current research findings and patents that highlight its emulsifying, stabilizing, film forming, and thickening properties. Hupu gum is a tree exudate from Cochlospermum religiosum belonging to the family Bixaceae. It is traditionally used for various medicinal and industrial purposes as it has a unique chemical composition and physical properties. Moreover, the current research and use of hupu gum as a biopolymer in the formulation and stabilization of nanoparticles (NP) is expanding the application spectrum of hupu gum. This writeup typically conclude with insights into future research directions, such as, exploring new applications, or enhancing its functional properties through modification.

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综述胡柚胶的新型药物应用:一种多功能天然聚合物。
对具有各种理化特性、可用于各种新型给药系统的天然辅料进行制药研究的兴趣与日俱增。受消费者对天然和可持续成分日益增长的偏好推动,hupu 胶(kondagogu 胶)等天然树胶的市场在全球范围内不断增长。本综述介绍了胡柚胶的植物起源、地理分布、化学成分、鉴定测试、毒理学研究以及在新型给药系统中的潜在应用。重点介绍了其在本土医药中的传统用途,以及突出其乳化、稳定、成膜和增稠特性的当前研究成果和专利。Hupu 树胶是一种从属于 Bixaceae 的 Cochlospermum religiosum 中提取的树木渗出物。由于它具有独特的化学成分和物理特性,传统上被用于各种医药和工业用途。此外,目前将胡柚胶作为一种生物聚合物用于纳米颗粒(NP)的配制和稳定的研究正在扩大胡柚胶的应用范围。本文最后将对未来的研究方向提出见解,如探索新的应用或通过改性提高其功能特性。
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来源期刊
Annales pharmaceutiques francaises
Annales pharmaceutiques francaises PHARMACOLOGY & PHARMACY-
CiteScore
1.70
自引率
7.70%
发文量
98
期刊介绍: This journal proposes a scientific information validated and indexed to be informed about the last research works in all the domains interesting the pharmacy. The original works, general reviews, the focusing, the brief notes, subjected by the best academics and the professionals, propose a synthetic approach of the last progress accomplished in the concerned sectors. The thematic Sessions and the – life of the Academy – resume the communications which, presented in front of the national Academy of pharmacy, are in the heart of the current events.
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