Harsha Sanaka, Elio Haroun, Aro Daniela Arockiam, Tiffany Dong, Allan Klein, Tom Kai Ming Wang
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引用次数: 0
Abstract
Purpose of review: To outline recent advances in imaging and treatment for recurrent pericarditis (RP).
Recent findings: Greater understanding of NLRP3 inflammasome activation in the pathogenesis of RP has led to the development of several anti-interleukin (IL-1) agents, and technological advancements have increased the utility of multimodality imaging in RP. Multimodality imaging plays a crucial role in the assessment of RP, with echocardiography serving as the initial imaging modality; cardiac magnetic resonance (CMR) as a pivotal test for diagnosis, grading severity, and surveillance; and cardiac computed tomography (CT) providing complimentary information and assisting operative assessment. Anti-IL-1 agents are now well-established as second line therapy for RP, with recent clinical trials demonstrating their efficacy.
综述的目的：概述复发性心包炎（RP）成像和治疗的最新进展：随着对NLRP3炎性体激活在RP发病机制中的作用的进一步了解，开发出了多种抗白细胞介素（IL-1）药物，而技术的进步也提高了多模态成像在RP中的应用。多模态成像在 RP 的评估中起着至关重要的作用，其中超声心动图是初始成像模式；心脏磁共振（CMR）是诊断、严重程度分级和监测的关键检查；心脏计算机断层扫描（CT）提供补充信息并协助手术评估。抗IL-1药物作为RP的二线疗法现已得到广泛认可，最近的临床试验也证明了其疗效。
期刊介绍：
The aim of this journal is to provide timely perspectives from experts on current advances in cardiovascular medicine. We also seek to provide reviews that highlight the most important recently published papers selected from the wealth of available cardiovascular literature.
We accomplish this aim by appointing key authorities in major subject areas across the discipline. Section editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.
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