The potential antibacterial effects of tea polyphenols.

Q2 Pharmacology, Toxicology and Pharmaceutics Drug metabolism and personalized therapy Pub Date : 2024-09-13 eCollection Date: 2024-09-01 DOI:10.1515/dmpt-2024-0058
Aparna Shil, Arnab Banerjee, Jayati Roy, Manisha Pal, Debasmita Das, Rajarshi Paul, Bithin Kumar Maji, Mausumi Sikdar
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Abstract

The current review of tea and its parts is focused on the antibacterial properties, considering the possible applications and modes of action against bacterial illnesses. It shows the backdrop of antibiotic resistance and the huge demand for antibacterial treatments out there. From the interactions with bacterial components, the theory presented that tea polyphenols are antibacterial and therefore would be a substitute or supplementary therapy to the usual antibiotics. The study highlighted the role of tea polyphenols as potential antibacterial compounds that may interact with various bacterial components and different polyphenolic compounds occurring in tea. Future research directions may be directed toward testing more plant-based sources for antibacterial properties, in vivo validation of the studies, and possible synergistic effects with classical antibiotics. By addressing the controversies and disagreements involved, the present understanding of the topic of tea's antibacterial properties and enable the entry of new ways for fighting microorganisms resistant to antibiotics. In conclusion, this review adds to the growing body of evidence regarding the antimicrobial properties of tea and emphasizes the need for further studies that will allow the full exploitation of its therapeutic potential for countering the rising problem of antibiotic resistance in healthcare.

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茶多酚的潜在抗菌作用。
目前对茶叶及其成分的综述主要集中在抗菌特性上,考虑了其在抗击细菌性疾病方面的可能应用和作用模式。它显示了抗生素耐药性的背景和对抗菌治疗的巨大需求。从与细菌成分的相互作用来看,该理论认为茶多酚具有抗菌作用,因此可以作为常用抗生素的替代品或辅助疗法。这项研究强调了茶多酚作为潜在抗菌化合物的作用,它可能与各种细菌成分和茶叶中的不同多酚化合物相互作用。未来的研究方向可能是测试更多植物来源的抗菌特性、研究的体内验证以及与传统抗生素可能产生的协同效应。通过解决所涉及的争议和分歧,目前对茶叶抗菌特性这一主题的理解将有助于找到对抗抗生素耐药性微生物的新方法。总之,这篇综述补充了有关茶叶抗菌特性的越来越多的证据,并强调有必要开展进一步的研究,以充分挖掘茶叶的治疗潜力,应对医疗保健领域日益严重的抗生素耐药性问题。
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来源期刊
Drug metabolism and personalized therapy
Drug metabolism and personalized therapy Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
2.30
自引率
0.00%
发文量
35
期刊介绍: Drug Metabolism and Personalized Therapy (DMPT) is a peer-reviewed journal, and is abstracted/indexed in relevant major Abstracting Services. It provides up-to-date research articles, reviews and opinion papers in the wide field of drug metabolism research, covering established, new and potential drugs, environmentally toxic chemicals, the mechanisms by which drugs may interact with each other and with biological systems, and the pharmacological and toxicological consequences of these interactions and drug metabolism and excretion. Topics: drug metabolizing enzymes, pharmacogenetics and pharmacogenomics, biochemical pharmacology, molecular pathology, clinical pharmacology, pharmacokinetics and drug-drug interactions, immunopharmacology, neuropsychopharmacology.
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