Retraction Note: Clinical Application of Thyrotropin Receptor Antibodies.

IF 2 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM Hormone and Metabolic Research Pub Date : 2024-09-15 DOI:10.1055/a-2415-5376
Yang Yang, Huang Weipeng
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Abstract

This article has been retracted by Thieme and the Editor in Chief. This article was published in error and this retraction is thus not the result of any fault or action of the authors. The Publisher and Editor apologise for this mistake and any inconvenience caused by this error.

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促甲状腺激素受体抗体的临床应用。
促甲状腺激素受体抗体(TRAb)是巴塞杜氏病(GD)的特异性抗体,在GD的发病机制中起着至关重要的作用。最近,TRAb检测方法有了很大改进。本综述讨论了 TRAb 在甲状腺功能亢进症的鉴别诊断、GD 的预后、妊娠期和儿科 GD 以及 GD 相关眼病(GO)中的临床应用。除了经典的竞争检测和生物检测外,TRAb检测还出现了一种新的桥接检测方法。TRAb 是 GD 甲状腺功能亢进症的主要致病机制。治疗后的 GD 仍有很高的复发率,甚至会出现 TRAb 短期激增,导致 GO 迅速恶化。胎儿甲状腺肿可能与妊娠期母体TRAb升高有关,过度治疗可能导致胎儿甲状腺功能减退。小儿甲状腺肿大患者的TRAb较高,治疗缓解率低,而GO的表现不明显。TRAb与GO的活性和严重程度密切相关。目前,TRAb检测具有较高的特异性和灵敏度,可直接用于确定甲状腺功能亢进的病因。TRAb可用于预测药物治疗后GD的复发或RAI治疗后GO的进展。应定期测量妊娠期GD的TRAb,以指导抗甲状腺药物治疗,避免胎儿甲亢或甲减。监测小儿GD的TRAb有助于控制GO的进展。TRAb检测是治疗GO的重要指导。
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来源期刊
Hormone and Metabolic Research
Hormone and Metabolic Research 医学-内分泌学与代谢
CiteScore
3.80
自引率
0.00%
发文量
125
审稿时长
3-8 weeks
期刊介绍: Covering the fields of endocrinology and metabolism from both, a clinical and basic science perspective, this well regarded journal publishes original articles, and short communications on cutting edge topics. Speedy publication time is given high priority, ensuring that endocrinologists worldwide get timely, fast-breaking information as it happens. Hormone and Metabolic Research presents reviews, original papers, and short communications, and includes a section on Innovative Methods. With a preference for experimental over observational studies, this journal disseminates new and reliable experimental data from across the field of endocrinology and metabolism to researchers, scientists and doctors world-wide.
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