Reproductive health in women with ankylosing spondylitis: contraception and fertility. A narrative review.

IF 1.2 Q4 RHEUMATOLOGY Reumatismo Pub Date : 2024-09-11 DOI:10.4081/reumatismo.2024.1778
L Marin, A Andrisani
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引用次数: 0

Abstract

Objective: The knowledge of ankylosing spondylitis is rising, and more and more attention is being paid to the diagnosis of this pathology in females. The purpose of this narrative review is to emphasize the role of reproductive health in women with ankylosing spondylitis, with particular attention to contraception and fertility.

Methods: A comprehensive review of the literature was performed to evaluate the reproductive health of women with ankylosing spondylitis.

Results: Oral contraception has been shown to be safe in women with ankylosing spondylitis, with no contraceptive benefits that should be evaluated during counseling. In the literature, there is no strong data regarding fertility in women with ankylosing spondylitis. It seems that these women may have impaired fertility due to reduced ovarian reserve, pharmacological treatments, and reduced sexual activity due to the concern that offspring may contract the disease. A multidisciplinary approach is needed in these women to ensure an adequate evaluation of sexual activity as an important aspect of quality of life and to counsel regarding family planning to address patients' concerns on contraception, fertility desire, and fertility preservation.

Conclusions: Lifestyle factors should be investigated to improve fertility and disease activity without medications. Further trials are needed to investigate the reproductive health of women with ankylosing spondylitis.

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强直性脊柱炎妇女的生殖健康:避孕与生育。叙述性综述。
目的:人们对强直性脊柱炎的认识在不断提高,对女性强直性脊柱炎的诊断也越来越重视。本综述旨在强调生殖健康在强直性脊柱炎女性患者中的作用,尤其关注避孕和生育问题:方法:对文献进行全面回顾,评估强直性脊柱炎女性患者的生殖健康状况:结果:已证明口服避孕药对患有强直性脊柱炎的妇女是安全的,在咨询过程中应评估其避孕效果。文献中没有关于强直性脊柱炎妇女生育能力的有力数据。由于卵巢储备功能降低、药物治疗以及担心后代可能感染疾病而减少性活动,这些女性的生育能力似乎可能会受到影响。对这些妇女需要采取多学科方法,以确保对作为生活质量重要方面的性活动进行充分评估,并提供计划生育咨询,以解决患者对避孕、生育愿望和生育力保护的担忧:结论:应研究生活方式因素,以便在不使用药物的情况下改善生育能力和疾病活动。需要进一步开展试验,研究强直性脊柱炎女性患者的生殖健康。
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来源期刊
Reumatismo
Reumatismo RHEUMATOLOGY-
CiteScore
2.10
自引率
7.10%
发文量
20
审稿时长
10 weeks
期刊介绍: Reumatismo is the official Journal of the Italian Society of Rheumatology (SIR). It publishes Abstracts and Proceedings of Italian Congresses and original papers concerning rheumatology. Reumatismo is published quarterly and is sent free of charge to the Members of the SIR who regularly pay the annual fee. Those who are not Members of the SIR as well as Corporations and Institutions may also subscribe to the Journal.
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