Refractory solar lentigines successfully treated with 532-nm nanosecond Nd:YAG Vasculature Salvage Laser Surgery (VSLS) system: Case series.

IF 2 4区医学 Q3 DERMATOLOGY Skin Research and Technology Pub Date : 2024-09-01 DOI:10.1111/srt.70055

So Young Lee, Ka Ram Kim, Seunghyeon Kim, Hye Sung Han, Ji Yeon Hong, Joon Seok, Kui Young Park

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Abstract

Background: Solar lentigo, a common epidermal hyperpigmented lesion found in sun-exposed areas, results from the proliferation of melanocytes and the accumulation of melanin. Although various treatments for solar lentigo have been explored, they often lead to complications, including prolonged erythema and post-inflammatory hyperpigmentation (PIH), posing significant concerns.

Objectives and methods: This study evaluated the safety and efficacy of the Vasculature Salvage Laser Surgery (VSLS) system. We treated six Korean patients, each with solar lentigo, in a single session using the 532-nm nanosecond neodymium-doped yttrium aluminum garnet (Nd:YAG) VSLS system, with follow-up periods ranging from 3 to 10 weeks.

Results: The treatment led to the complete removal of pigmented lesions in all patients without resulting in PIH, even in cases where previous laser treatments had failed. The only side effect observed was mild erythema, which resolved over the long term in most instances.

Conclusions: The VSLS system emerges as a safe and effective treatment for pigmented lesions, including refractory solar lentigines. Nonetheless, additional studies are required to verify its long-term efficacy.

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使用 532 纳米 Nd:YAG 血管挽救激光手术（VSLS）系统成功治疗难治性日光性色素斑：病例系列。

背景：日光性白斑是一种常见的表皮色素沉着病变，多发于阳光暴露部位，是黑色素细胞增殖和黑色素堆积的结果。虽然已探索出多种治疗日光性白斑的方法，但这些方法往往会导致并发症，包括红斑持续时间延长和炎症后色素沉着（PIH），令人十分担忧：本研究评估了血管挽救激光手术（VSLS）系统的安全性和有效性。我们使用 532 纳米纳秒掺钕钇铝石榴石（Nd:YAG）VSLS 系统对六名韩国日光性白斑患者进行了单次治疗，随访时间为 3 至 10 周：结果：所有患者的色素性病变都得到了彻底清除，甚至在之前的激光治疗失败的病例中也没有出现 PIH。观察到的唯一副作用是轻微红斑，大多数情况下红斑会在长期治疗后消退：结论：VSLS 系统是治疗色素性病变（包括难治性日光性色斑）的一种安全有效的方法。尽管如此，还需要更多的研究来验证其长期疗效。

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来源期刊

Skin Research and Technology 医学-皮肤病学

CiteScore

3.30

自引率

9.10%

发文量

审稿时长

6-12 weeks

期刊介绍： Skin Research and Technology is a clinically-oriented journal on biophysical methods and imaging techniques and how they are used in dermatology, cosmetology and plastic surgery for noninvasive quantification of skin structure and functions. Papers are invited on the development and validation of methods and their application in the characterization of diseased, abnormal and normal skin. Topics include blood flow, colorimetry, thermography, evaporimetry, epidermal humidity, desquamation, profilometry, skin mechanics, epiluminiscence microscopy, high-frequency ultrasonography, confocal microscopy, digital imaging, image analysis and computerized evaluation and magnetic resonance. Noninvasive biochemical methods (such as lipids, keratin and tissue water) and the instrumental evaluation of cytological and histological samples are also covered. The journal has a wide scope and aims to link scientists, clinical researchers and technicians through original articles, communications, editorials and commentaries, letters, reviews, announcements and news. Contributions should be clear, experimentally sound and novel.