Unravelling diagnostic challenges: A case report of pulmonary langerhans cell histiocytosis with atypical radiologic presentation.

IF 0.8 Q4 RESPIRATORY SYSTEM Respirology Case Reports Pub Date : 2024-09-10 eCollection Date: 2024-09-01 DOI:10.1002/rcr2.70004
Joseph Inauen, Simone Barry
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Abstract

This clinical case highlights the diagnostic challenges encountered in a young adult smoker presenting with undifferentiated pulmonary nodules. Initial investigations were inconclusive, necessitating surgical lung biopsy due to the nodules' size and location. The histopathological examination revealed pulmonary Langerhans cell histiocytosis (PLCH). This emphasizes the importance of considering PLCH in the differential diagnosis of pulmonary nodules, particularly in smokers. Moreover, it underscores the value of surgical biopsy in cases where other diagnostic techniques are limited. Early recognition and accurate diagnosis are crucial for optimal management and outcomes in PLCH.

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破解诊断难题:一例放射学表现不典型的肺朗格汉斯细胞组织细胞增生症病例报告。
这个临床病例突出说明了一名年轻的成年吸烟者在诊断未分化肺结节时遇到的挑战。由于结节的大小和位置,最初的检查没有得出结论,必须进行外科肺活检。组织病理学检查发现了肺朗格汉斯细胞组织细胞增生症(PLCH)。这强调了在肺部结节的鉴别诊断中考虑 PLCH 的重要性,尤其是在吸烟者中。此外,它还强调了在其他诊断技术有限的情况下进行手术活检的价值。早期识别和准确诊断对于 PLCH 的最佳治疗和预后至关重要。
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来源期刊
Respirology Case Reports
Respirology Case Reports RESPIRATORY SYSTEM-
CiteScore
1.40
自引率
0.00%
发文量
178
审稿时长
8 weeks
期刊介绍: Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.
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