Major Determinants of Well-Being in Patients With Axial Spondyloarthritis: 2 Year Follow-Up.

IF 1.5 Q3 RHEUMATOLOGY Musculoskeletal Care Pub Date : 2024-09-01 DOI:10.1002/msc.1942

Elif Durak Ediboglu, Esra Erpek, Deniz Bayraktar, Mustafa Özmen, Dilek Solmaz, Servet Akar

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Abstract

Objectives: Bath Ankylosing Spondylitis Patient Global Score (BAS-G) is a uni-dimensional scale that enables patients to evaluate the effects of their illness on their health. The aim of this study was to determine the impact of disease related outcomes on the BAS-G scores in patients with axSpA.

Methods: A total of 309 patients (56.6% of whom were male, mean age 44 ± 11) were included in the study. Socio-demographic characteristics (age, sex and education level) and clinical characteristics such as disease activity (BASDAI and CRP), spinal mobility (BASMI), functional status (BASFI), radiographic structural damage (mSASS, mNY, and BASRI-hip), and health related quality of life (SF-36 and ASQoL) of the patients were recorded at baseline. In addition, BASDAI total and each item score, BASFI, BAS-G, and CRP levels were collected at 6, 12, and 24 months.

Results: Female patients had significantly higher BAS-G scores (p = 0.037). Baseline BASDAI total score (p < 0.001) and all BASDAI item scores (p < 0.001 for each item), BASFI total score (p < 0.001), ASQoL total score (p < 0.001), and SF-36 PCS sum-score (p < 0.001) were moderately/highly correlated with BAS-G. Multivariate analysis revealed that back pain (BASDAI Q2) (p < 0.001) and the severity of morning stiffness (BASDAI Q5) (p < 0.001) were the main determinants of BAS-G in patients with axSpA. In 2-year follow-up, BASDAI Q1, BASDAI Q5, and BASFI scores were independent determinants of BAS-G in patients with axSpA.

Conclusion: According to the results of the present study, patients with axSpA mainly rely on morning stiffness and back pain to determine their global health status. Moreover, fatigue, severity of morning stiffness and function are the determinants of BAS-G during follow-up.

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轴性脊椎关节炎患者幸福感的主要决定因素：两年随访。

目的：巴斯-强直性脊柱炎患者综合评分（BAS-G）是一种单维度量表，可帮助患者评估疾病对其健康的影响。本研究旨在确定疾病相关结果对 axSpA 患者 BAS-G 评分的影响：研究共纳入 309 名患者（其中 56.6% 为男性，平均年龄（44 ± 11）岁）。基线时记录了患者的社会人口学特征（年龄、性别和教育水平）和临床特征，如疾病活动度（BASDAI 和 CRP）、脊柱活动度（BASMI）、功能状态（BASFI）、影像学结构损伤（mSASS、mNY 和 BASRI-hip）以及与健康相关的生活质量（SF-36 和 ASQoL）。此外，还收集了 6、12 和 24 个月时的 BASDAI 总分和各项目得分、BASFI、BAS-G 和 CRP 水平：结果：女性患者的 BAS-G 评分明显更高（p = 0.037）。结果：女性患者的 BAS-G 评分明显更高（P = 0.037），基线 BASDAI 总分（P根据本研究的结果，axSpA 患者主要依靠晨僵和背痛来判断其总体健康状况。此外，疲劳、晨僵严重程度和功能是随访期间 BAS-G 的决定因素。

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来源期刊

Musculoskeletal Care RHEUMATOLOGY-

CiteScore

2.30

自引率

7.70%

发文量

期刊介绍： Musculoskeletal Care is a peer-reviewed journal for all health professionals committed to the clinical delivery of high quality care for people with musculoskeletal conditions and providing knowledge to support decision making by professionals, patients and policy makers. This journal publishes papers on original research, applied research, review articles and clinical guidelines. Regular topics include patient education, psychological and social impact, patient experiences of health care, clinical up dates and the effectiveness of therapy.