[A PhD completed. Oral manifestations in inflammatory bowel diseases].

C X W Tan, H S Brand, K H N de Boer, J G A M de Visscher
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Abstract

Crohn's disease and ulcerative colitis are chronic inflammatory diseases of the gastrointestinal tract. In addition to bowel symptoms, patients may also have oral manifestations. This thesis investigated potential associations between disease activity in the gut, oral health, salivary gland function, and saliva composition. Patients with Crohn's disease had a significantly higher DMFT index, but showed no difference in periodontal diseases compared to a healthy control group. The saliva composition in patients with active bowel disease differed from that in patients with inactive bowel disease, suggesting that saliva analysis could potentially be used in the future to determine the degree and severity of bowel disease. The knowledge of gastroenterologists and dentists regarding oral manifestations of bowel diseases was found to be limited. Gastroenterologists and dentists valued interdisciplinary patient consultation as very useful, but the frequency of consultation was considered insufficient.

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[炎症性肠病的口腔表现]。
克罗恩病和溃疡性结肠炎是胃肠道的慢性炎症性疾病。除肠道症状外,患者还可能有口腔表现。本论文研究了肠道疾病活动、口腔健康、唾液腺功能和唾液成分之间的潜在关联。克罗恩病患者的 DMFT 指数明显较高,但与健康对照组相比,他们的牙周疾病并无差异。活动性肠病患者的唾液成分与非活动性肠病患者的唾液成分不同,这表明唾液分析将来有可能用于确定肠病的程度和严重性。研究发现,肠胃病学家和牙科医生对肠道疾病的口腔表现了解有限。胃肠病学家和牙科医生认为跨学科病人咨询非常有用,但认为咨询的频率不够。
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