Burkitt lymphoma manifested by initial oral and maxillofacial lesions: a case report in a child patient and review of related articles.

Hong Wu, Wenhui Zhao, Xiaoqian Yang, Xiuli Li, Yanrong Zhang, Aimei Song
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Abstract

Burkitt lymphoma is a highly aggressive B-cell lymphoma and the fastest proliferating human malignant tumor. If the disease is found in the early stage, the patient could have a high possibility to be cured successfully, whereas the prognosis is poor in the late stage. Burkitt lymphoma can occur in children and adults, and it is categorized as local (Africa), sporadic, and immunodeficiency associated type. Sporadic Burkitt lymphoma mainly affects children and adolescents, and the most common initial sites are abdominal organs and lymph nodes. Sporadic Burkitt lymphoma manifested by initial oral and maxillofacial lesions is relatively rare. Here, a case of pediatric sporadic Burkitt lymphoma, with oral and maxillofacial lesions as the first symptoms, was reported. The patient was treated in the Department of Periodontology, Shandong University School and Hospital of Stomatology. After timely checkup was provided, the patient was transferred to another hospital and had good results. In this article, an incidence of Burkitt lymphoma, with oral and maxillofacial lesions as the first symptom, was reviewed to provide reference for oral clinicians to achieve early diagnosis and treatment of patients with Burkitt lymphoma with oral diseases and improve the success rate of treatment.

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以初始口腔和颌面部病变为表现的伯基特淋巴瘤:一例儿童患者的病例报告及相关文章综述。
伯基特淋巴瘤是一种侵袭性极强的B细胞淋巴瘤,也是增殖速度最快的人类恶性肿瘤。如果在早期发现,患者成功治愈的可能性很大,而晚期预后较差。伯基特淋巴瘤可发生于儿童和成人,分为局部型(非洲)、散发性和免疫缺陷相关型。散发性伯基特淋巴瘤主要影响儿童和青少年,最常见的初发部位是腹部器官和淋巴结。以口腔和颌面部病变为首发表现的散发性伯基特淋巴瘤相对罕见。本文报告了一例以口腔和颌面部病变为首发症状的小儿散发性伯基特淋巴瘤。患者在山东大学口腔医学院附属医院牙周科接受治疗。经及时检查后,患者转院治疗,效果良好。本文回顾了以口腔颌面部病变为首发症状的伯基特淋巴瘤的发病情况,为口腔临床医生实现伯基特淋巴瘤合并口腔疾病患者的早诊早治,提高治疗成功率提供参考。
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