Stellate Ganglion Blocks for Post-Traumatic Stress Disorder: A Review of Mechanisms, Efficacy, and Complications.

Psychopharmacology bulletin Pub Date : 2024-08-19

Jamal Hasoon, Sana Sultana, Aila Malik, Patrick Brown, Alexa Ryder, Christopher L Robinson, Ivan Urits, Giustino Varrassi, Omar Viswanath

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Abstract

Post-traumatic stress disorder (PTSD) stands as a pervasive psychiatric condition, exerting a profound impact on millions across the globe. Despite the availability of traditional therapeutic modalities, many individuals continue to grapple with suboptimal treatment outcomes, underscoring the urgent need for novel interventions. In recent years, stellate ganglion blocks (SGBs) have garnered attention as a promising avenue in the treatment landscape for PTSD, showcasing remarkable efficacy in ameliorating symptomatology and enhancing overall quality of life. This comprehensive review seeks to delve into the current landscape of research surrounding SGBs for PTSD, including proposed mechanisms of action, clinical efficacy across diverse patient populations, safety profile, and potential avenues for further exploration and refinement. By synthesizing the latest evidence and insights, this review aims to provide clinicians and researchers with a comprehensive understanding of the role of SGBs in PTSD management, ultimately informing clinical practice and guiding future research endeavors in this area of mental health intervention.

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星状神经节阻滞治疗创伤后应激障碍：机制、疗效和并发症综述》。

创伤后应激障碍（PTSD）是一种普遍存在的精神疾病，对全球数百万人造成了深远的影响。尽管有传统的治疗方法，但许多人仍然无法获得理想的治疗效果，这凸显了对新型干预措施的迫切需求。近年来，星状神经节阻滞疗法（SGBs）作为创伤后应激障碍治疗领域的一种前景广阔的疗法备受关注，在改善症状和提高整体生活质量方面显示出显著疗效。本综述旨在深入探讨目前围绕 SGBs 治疗创伤后应激障碍的研究现状，包括拟议的作用机制、对不同患者群体的临床疗效、安全性以及进一步探索和完善的潜在途径。通过综合最新的证据和见解，本综述旨在让临床医生和研究人员全面了解 SGBs 在创伤后应激障碍治疗中的作用，最终为临床实践提供依据，并指导这一心理健康干预领域未来的研究工作。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Psychopharmacology bulletin

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