Prevalence of glaucoma in Canada: results from the 2016-2019 Canadian Health Measures Survey.

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-09-20 DOI:10.1016/j.jcjo.2024.08.016
Ya-Ping Jin, Kiko Zi Yi Huang, Qingqing K Zhao, Graham E Trope, Yvonne M Buys, Sherif El-Defrawy, Peng Yan, Michael H Brent, Ziad Butty
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Abstract

Objective: To estimate the prevalence of glaucoma in Canada based on self-reports and test data, including Frequency Doubling Technology Perimetry (FDT), optic nerve vertical cup-to-disc ratio (CDR), intraocular pressure (IOP), and use of glaucoma medications.

Design: Cross-sectional survey.

Participants: 2,600-4,100 participants aged 40-79 in the Canadian Health Measures Survey 2016-2019 with available information from self-report, CDR, FDT, and IOP.

Methods: Glaucoma was defined by self-reports, CDR ≥ 0.7 only, or failed FDT only. Incorporating results of CDR, FDT, IOP, and use of glaucoma medications, participants were further classified as definite glaucoma (failed FDT and CDR ≥ 0.7) or glaucoma suspects (CDR ≥ 0.7 only, failed FDT only, or IOP > 21 mmHg only, or "normal" values of FDT, CDR, and IOP but used glaucoma medications). Survey weights were used in analyses.

Results: The glaucoma prevalence was 2.5% (95% confidence interval [CI] 1.7%-3.3%) utilizing self-reports, 3.0% (95% CI 2.1%-3.9%) by CDR ≥ 0.7 only and 10.3% (7.8%-12.8%) with failed FDT only. Merging test data, the prevalence of definite glaucoma was 0.7% (95% CI 0.3%-1.1%) and the prevalence of suspected glaucoma was 16.3% (95% CI 13.2%-19.4%). Among the patients suspected of having glaucoma, 44.4% had ocular hypertension (OHT, mean IOP 22.8 mmHg) and 6.8% used glaucoma medications. IOP ≥28 mmHg was found in 2.4% of OHT individuals, and none used glaucoma medications.37.5% of Canadians with definite glaucoma were unaware they had glaucoma.

Conclusions: Glaucoma prevalence in Canadians aged 40-79 varied between 0.7% and 10.3% depending on definition used. 16.3% of Canadians were labeled "glaucoma suspects". Nearly 40% of Canadians with definite glaucoma were unaware of having glaucoma.

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加拿大青光眼患病率:2016-2019 年加拿大健康措施调查结果。
目的:根据自我报告和测试数据(包括倍频技术验光法(FDT)、视神经垂直杯盘比(CDR)、眼压(IOP)和青光眼药物使用情况)估算加拿大青光眼患病率:横断面调查。参与者:2016-2019 年加拿大健康措施调查中年龄在 40-79 岁之间的 2,600-4,100 名参与者,其信息来自自我报告、CDR、FDT 和 IOP:青光眼的定义是自我报告、CDR≥0.7或FDT失败。结合CDR、FDT、眼压和青光眼药物的使用情况,进一步将参与者分为明确的青光眼(FDT失败且CDR≥0.7)或疑似青光眼(仅CDR≥0.7,仅FDT失败,或仅眼压>21 mmHg,或FDT、CDR和眼压值 "正常 "但使用青光眼药物)。分析中使用了调查权重:利用自我报告的青光眼患病率为 2.5%(95% 置信区间 [CI] 1.7%-3.3%),仅 CDR ≥ 0.7 的患病率为 3.0%(95% 置信区间 [CI] 2.1%-3.9%),仅 FDT 失败的患病率为 10.3%(7.8%-12.8%)。合并检测数据后,确诊青光眼的患病率为 0.7%(95% CI 0.3%-1.1%),疑似青光眼的患病率为 16.3%(95% CI 13.2%-19.4%)。在疑似青光眼患者中,44.4%患有眼压过高(OHT,平均眼压 22.8 mmHg),6.8%使用青光眼药物。2.4%的 OHT 患者眼压≥28 mmHg,但没有人使用青光眼药物。37.5%患有明确青光眼的加拿大人不知道自己患有青光眼:结论:40-79 岁加拿大人中青光眼的发病率在 0.7% 到 10.3% 之间,具体取决于所使用的定义。16.3%的加拿大人被称为 "青光眼疑似患者"。在确诊患有青光眼的加拿大人中,有近 40% 的人不知道自己患有青光眼。
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