Associations Between Cardiovascular Health (Life's Essential 8) and Mental Disorders

IF 2.4 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Clinical Cardiology Pub Date : 2024-09-24 DOI:10.1002/clc.70019
Yudi Xu, Wenjing Ning, Yuyuan Zhang, Yuhao Ba, Huimin Liu, Long Liu, Libo Wang, Chunguang Guo, Hui Xu, Siyuan Weng, Zhaokai Zhou, Zongao Cai, Hongxuan Ma, Ge Zhang, Yanjie Jia, Xinwei Han
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Abstract

Background

Mental health was closely associated with cardiovascular disease (CVD). We aimed to investigate the association between cardiovascular health (CVH), as defined by Life's Essential 8 (LE8), and the presence of depression and anxiety.

Hypothesis

We hypothesized that CVH, as defined by LE8, was negatively associated with the prevalence of depression and anxiety.

Methods

A cross-sectional study was conducted on participants (≥ 20 years old) from the National Health and Nutrition Examination Survey (NHANES). The LE8 score (ranging from 0 to 100) was composed of the health behavior score and the health factor score, which were further categorized into three levels as follows: low (0–49), moderate (50–79), and high (80–100). Weighted multivariable logistic regressions and restricted cubic splines were utilized to assess the association between LE8 and mental disorders.

Results

Among the 13 028 participants included in this research, 1206 were determined to have depression symptoms and 2947 were determined to have anxiety symptoms. In the weighted and adjusted model, LE8 was negatively associated with the prevalence of depression (odds ratio [OR], 95% confidence interval [CI]: 0.61, 0.58–0.65) and anxiety (OR, 95% CI: 0.78, 0.75–0.81). Furthermore, a nonlinear dose–response relationship was observed between LE8 and anxiety.

Conclusions

CVH defined by the LE8 was independently and negatively associated with the prevalence of depression and anxiety. Interventions targeting LE8 components may improve both CVH and mental health.

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心血管健康(人生必修 8)与精神障碍之间的关系。
背景:心理健康与心血管疾病(CVD)密切相关。我们的目的是调查生命必备 8(LE8)所定义的心血管健康(CVH)与抑郁和焦虑之间的关系:我们假设,LE8 所定义的心血管健康与抑郁和焦虑的发生率呈负相关:我们对美国国家健康与营养调查(NHANES)的参与者(≥ 20 岁)进行了一项横断面研究。LE8得分(从0到100分不等)由健康行为得分和健康因素得分组成,并进一步分为以下三个等级:低(0-49分)、中(50-79分)和高(80-100分)。利用加权多变量逻辑回归和限制性三次样条来评估LE8与精神障碍之间的关系:在 13 028 名参与研究的人员中,有 1206 人被确定有抑郁症状,2947 人被确定有焦虑症状。在加权调整模型中,LE8 与抑郁症(几率比[OR],95% 置信区间[CI]:0.61,0.58-0.65)和焦虑症(几率比,95% 置信区间[CI]:0.78,0.75-0.81)的患病率呈负相关。此外,LE8与焦虑之间还存在非线性剂量反应关系:结论:LE8所定义的CVH与抑郁和焦虑的发生率呈负相关。针对 LE8 成分的干预措施可同时改善 CVH 和心理健康。
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来源期刊
Clinical Cardiology
Clinical Cardiology 医学-心血管系统
CiteScore
5.10
自引率
3.70%
发文量
189
审稿时长
4-8 weeks
期刊介绍: Clinical Cardiology provides a fully Gold Open Access forum for the publication of original clinical research, as well as brief reviews of diagnostic and therapeutic issues in cardiovascular medicine and cardiovascular surgery. The journal includes Clinical Investigations, Reviews, free standing editorials and commentaries, and bonus online-only content. The journal also publishes supplements, Expert Panel Discussions, sponsored clinical Reviews, Trial Designs, and Quality and Outcomes.
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