Nutritional and psychological sequelae of COVID-19 infection in maintenance hemodialysis patients.

IF 1.1 4区 医学 Q3 UROLOGY & NEPHROLOGY Clinical nephrology Pub Date : 2024-09-24 DOI:10.5414/CN111369
Sara T Ibrahim, Basant M Talaat, Iman E ElGohary, Gihane I Khalil, Dalia A Maharem
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引用次数: 0

Abstract

Aim: The risk of infection with COVID-19 in hemodialysis (HD) patients is higher compared to the general population. Additionally, HD patients are at higher risk of developing post-COVID-19 infection sequelae. However, this has not been thoroughly investigated. Therefore, we aimed to study the impact of COVID-19 on nutritional status and psychological health in HD patients 6 months following recovery.

Materials and methods: We recruited HD patients who were proven to be infected with COVID-19 and received treatment at two HD units in two institutions between April 2022 and December 2022. Additionally, we enrolled a group of age- and sex-matched HD patients who had not previously been infected with COVID-19 or received vaccination. Nutritional status was assessed using malnutrition inflammation score (MIS), while psychological health was assessed using online questionnaires. The Patient Health Questionnaire 9 (PHQ 9) was employed to assess symptoms of depression, the Generalized Anxiety Disorder 7 (GAD 7) was used to identify anxiety disorders, the Patient Health Questionnaire 15 (PHQ 15) was utilized to measure somatic symptoms, and the Insomnia Severity Index (ISI) was used to measure insomnia.

Results: A total of 60 subjects (30 patients and 30 controls) were assessed in the study. We found statistically significant differences between patients and controls regarding the MIS (median score (interquartile range (IQR)); 11 (9 - 12) and 5.5 (5 - 7), respectively), PHQ 15 (median score (IQR); 17.5 (15 - 19) and 9 (6 - 11), respectively), PHQ 9 (median score (IQR); 17 (13 - 19) and 5 (7 - 8), respectively), GAD 7 (median score (IQR); 14 (11 - 16) and 6 (4 - 8), respectively), and ISI (median score (IQR); 20 (15 - 22) and 8 (7 - 11), respectively), with p < 0.001 for all scores.

Conclusion: COVID-19 has long-term effects on the psychosocial health of HD patients and may lead to a higher incidence of malnutrition 6 months post recovery.

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维持性血液透析患者感染 COVID-19 后的营养和心理后遗症。
目的:与普通人群相比,血液透析(HD)患者感染 COVID-19 的风险更高。此外,血液透析患者发生 COVID-19 感染后遗症的风险更高。然而,这一点尚未得到深入研究。因此,我们旨在研究 COVID-19 对 HD 患者康复后 6 个月的营养状况和心理健康的影响:我们招募了 2022 年 4 月至 2022 年 12 月期间被证实感染 COVID-19 并在两家机构的两家 HD 单位接受治疗的 HD 患者。此外,我们还招募了一组年龄和性别匹配的 HD 患者,他们之前未感染 COVID-19,也未接种疫苗。营养状况通过营养不良炎症评分(MIS)进行评估,心理健康则通过在线问卷进行评估。患者健康问卷9(PHQ 9)用于评估抑郁症状,广泛性焦虑症7(GAD 7)用于识别焦虑症,患者健康问卷15(PHQ 15)用于测量躯体症状,失眠严重程度指数(ISI)用于测量失眠:研究共评估了 60 名受试者(30 名患者和 30 名对照组)。我们发现,患者和对照组在失眠症严重程度指数(MIS)(中位数分数(四分位距);分别为 11 (9 - 12) 和 5.5 (5 - 7))、PHQ 15(中位数分数(四分位距);分别为 17.5(15 - 19)和 9(6 - 11))、PHQ 9(中位数分数(IQR);分别为 17(13 - 19)和 5(7 - 8))、GAD 7(中位数分数(IQR);分别为 14(11 - 16)和 6(4 - 8))和 ISI(中位数分数(IQR);分别为 20(15 - 22)和 8(7 - 11)),P 结论:COVID-19 对 HD 患者的社会心理健康有长期影响,并可能导致康复后 6 个月营养不良的发生率升高。
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来源期刊
Clinical nephrology
Clinical nephrology 医学-泌尿学与肾脏学
CiteScore
2.10
自引率
9.10%
发文量
138
审稿时长
4-8 weeks
期刊介绍: Clinical Nephrology appears monthly and publishes manuscripts containing original material with emphasis on the following topics: prophylaxis, pathophysiology, immunology, diagnosis, therapy, experimental approaches and dialysis and transplantation.
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