Role of sarcopenia in complex abdominal wall surgery: does it increase postoperative complications and mortality?

IF 2.6 2区 医学 Q1 SURGERY Hernia Pub Date : 2024-09-24 DOI:10.1007/s10029-024-03174-x
Ángela Santana Valenciano, Luis Blázquez Hernando, Álvaro Robín Valle de Lersundi, Javier López Monclús, Joaquín Muñoz Rodríguez, Belén Porrero Guerrero, Laura Román García de León, José Manuel Molina Villar, Manuel Medina Pedrique, Javier Blázquez Sánchez, José María Fernández Cebrián, Miguel Ángel García Ureña
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Abstract

Background: Sarcopenia is defined as the loss of skeletal muscle mass and is associated with an increased risk or morbidity and mortality in complex surgical patient populations. Its role in complex abdominal wall surgery (AWS) is yet to be determined. The aim of this study is to establish if sarcopenia has an impact on postoperative complications, mortality and hernia recurrence.

Methods: Retrospective study of patients undergoing elective surgery for complex incisional hernias > 10 cm (W3 of European Hernia Society classification) between 2014-2023. Sarcopenia was stablished as the skeletal muscle index (SMI), measured at L3 transversal section of a preoperative CT-scan. Previously defined literature-based SMI cutoff values were used: men ≤ 52.4 cm2/m2, women ≤ 38.5 cm2/m2.

Results: 135 patients undergoing complex AWS were included. Of them, 38 were sarcopenic (28.1%). The median follow-up time was 13 months (IQR 12-25). In total, 11 patients died (8.1%). We found that sarcopenia was associated with a higher risk of mortality [HR 7.494 (95% CI 1.985-28.289); p 0.003]. There were no statistically significant differences in postoperative complications or hernia recurrence between both groups.

Conclusion: Although sarcopenia does not seem to have an influence on hernia recurrence or the development of postoperative complications, whether local or systemic, in our study sarcopenia is associated with a higher risk of mortality after complex abdominal wall surgery. Nonetheless, with the results obtained in our study, we think that prehabilitation programs before complex AWS is advisable.

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肌肉疏松症在复杂腹壁手术中的作用:会增加术后并发症和死亡率吗?
背景:肌肉疏松症被定义为骨骼肌质量的丧失,与复杂手术患者发病率和死亡率的增加有关。其在复杂腹壁手术(AWS)中的作用尚待确定。本研究旨在确定肌肉疏松症对术后并发症、死亡率和疝气复发是否有影响:方法:对2014-2023年间因复杂切口疝大于10厘米(欧洲疝气协会分类W3)而接受择期手术的患者进行回顾性研究。根据术前CT扫描L3横断面测量的骨骼肌指数(SMI)确定 "肌肉疏松症"。采用了之前基于文献定义的 SMI 临界值:男性 ≤ 52.4 cm2/m2,女性 ≤ 38.5 cm2/m2:结果:共纳入 135 名接受复杂 AWS 的患者。结果:共纳入 135 名接受复杂 AWS 的患者,其中 38 人(28.1%)为肌无力患者。中位随访时间为 13 个月(IQR 12-25)。共有 11 名患者死亡(8.1%)。我们发现,肌肉疏松症与较高的死亡风险相关[HR 7.494 (95% CI 1.985-28.289); p 0.003]。两组患者在术后并发症或疝气复发方面的差异无统计学意义:尽管肌肉疏松症似乎对疝气复发或术后并发症(无论是局部还是全身性)的发生没有影响,但在我们的研究中,肌肉疏松症与复杂腹壁手术后较高的死亡风险有关。尽管如此,根据我们的研究结果,我们认为在进行复杂腹壁手术前进行术前康复训练是可取的。
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来源期刊
Hernia
Hernia SURGERY-
CiteScore
4.90
自引率
26.10%
发文量
171
审稿时长
4-8 weeks
期刊介绍: Hernia was founded in 1997 by Jean P. Chevrel with the purpose of promoting clinical studies and basic research as they apply to groin hernias and the abdominal wall . Since that time, a true revolution in the field of hernia studies has transformed the field from a ”simple” disease to one that is very specialized. While the majority of surgeries for primary inguinal and abdominal wall hernia are performed in hospitals worldwide, complex situations such as multi recurrences, complications, abdominal wall reconstructions and others are being studied and treated in specialist centers. As a result, major institutions and societies are creating specific parameters and criteria to better address the complexities of hernia surgery. Hernia is a journal written by surgeons who have made abdominal wall surgery their specific field of interest, but we will consider publishing content from any surgeon who wishes to improve the science of this field. The Journal aims to ensure that hernia surgery is safer and easier for surgeons as well as patients, and provides a forum to all surgeons in the exchange of new ideas, results, and important research that is the basis of professional activity.
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