A novel technique for skull base reconstruction in craniofacial fibrous dysplasia surgery using three-dimensional printing and a dental alginate mold: illustrative case.

Kirby C Manigos, Joseph Erroll V Navarro, Kenny S Seng, Jose Carlos S Alcazaren, Oliver Ryan M Malilay, Tito Guillermo D Rejante, Kevin Paul Ferraris
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Abstract

Background: Fibrous dysplasia is a rare and benign skeletal lesion characterized by fibrous tissue proliferation due to an abnormal osteogenesis replacing normal bone.

Observations: An 18-year-old male with fibrous dysplasia of the left sphenoid, ethmoid, orbit, and frontal bones was managed with excision and skull base reconstruction. After complete removal of the tumor, skull base reconstruction was commenced by making a reverse temporalis flap and placing it over the opened paranasal sinuses for a robust vascularized graft, followed by an abdominal fat graft, and then a pedicled pericranal flap was added to complete the multilayer onlay graft. To recreate the skull base, a mirror image of the contralateral skull base was constructed using three-dimensional (3D) printing, and the 3D-printed model was sterilized prior to the surgery. Intraoperatively, the model was then pressed onto dental alginate gel to make a negative mold. This was used to make the definitive flap using polymethylmethacrylate. Temporoplasty was also performed using polymethylmethacrylate to fill the defect left by the temporalis graft. The patient recovered well following the procedure.

Lessons: Appropriate, personalized skull base reconstruction techniques can be successfully done with 3D printing using alternative low-cost materials and implements, especially following resection of cases like craniofacial fibrous dysplasia. https://thejns.org/doi/10.3171/CASE24262.

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利用三维打印和牙科藻酸盐模具在颅面纤维发育不良手术中重建颅底的新技术:示例。
背景:纤维性发育不良是一种罕见的良性骨骼病变,其特点是由于异常成骨作用导致纤维组织增生,取代正常骨骼:一名 18 岁男性的左侧蝶骨、乙状骨、眼眶和额骨纤维性发育不良患者接受了切除术和颅底重建术。完全切除肿瘤后,开始进行颅底重建,首先制作反向颞肌皮瓣,并将其置于打开的副鼻窦上,以形成稳固的血管移植物,然后进行腹部脂肪移植物,最后再加上有蒂的颅周皮瓣,以完成多层嵌合移植物。为了再造颅底,使用三维(3D)打印技术构建了对侧颅底的镜像,并在手术前对3D打印模型进行了消毒。术中,模型被压在牙科藻酸盐凝胶上,制成阴模。然后使用聚甲基丙烯酸甲酯制作最终皮瓣。此外,还使用聚甲基丙烯酸甲酯进行了颞成形术,以填补颞肌移植后留下的缺损。术后患者恢复良好:https://thejns.org/doi/10.3171/CASE24262。
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