{"title":"The changing face of HIV pathology: a personal perspective","authors":"Sebastian Lucas","doi":"10.1016/j.mpdhp.2024.07.006","DOIUrl":null,"url":null,"abstract":"<div><div>Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) became a significant new disease complex in the 1980s. The wide range of associated pathologies came from pathological observation of living and dead patients. The opportunistic infections and cancers, systemic wasting syndromes and direct HIV-induced damage to most organs are well described, but new syndromes will probably emerge. The major change in HIV clinical pathology happened after 1996 when effective anti-HIV chemotherapy became available and AIDS ceased to be a death sentence. Complications of the new therapies will continue to present, requiring vigilance.</div></div>","PeriodicalId":39961,"journal":{"name":"Diagnostic Histopathology","volume":"30 10","pages":"Pages 576-587"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic Histopathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1756231724001130","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) became a significant new disease complex in the 1980s. The wide range of associated pathologies came from pathological observation of living and dead patients. The opportunistic infections and cancers, systemic wasting syndromes and direct HIV-induced damage to most organs are well described, but new syndromes will probably emerge. The major change in HIV clinical pathology happened after 1996 when effective anti-HIV chemotherapy became available and AIDS ceased to be a death sentence. Complications of the new therapies will continue to present, requiring vigilance.
期刊介绍：
This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.
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