Assessment of acute poisoning in children using poisoning severity scores: A cross-sectional study at Damietta General Hospital Egypt

Q1 Environmental Science Toxicology Reports Pub Date : 2024-09-13 DOI:10.1016/j.toxrep.2024.101735
Heba Youssef Sayed , Rana Elawady , Mona Ibrahim Elyamany , Mohamed S. Hemeda
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Abstract

Acute poisoning is a prevalent health issue, particularly among children, due to their natural curiosity and tendency to explore. This cross-sectional study aimed to evaluate the characteristics, causes, clinical presentation, and outcomes of acute intoxication in children at Damietta General Hospital, Egypt. We included 106 pediatric patients (aged under 18 years) with a clear history or clinical signs of acute poisoning. Data collection encompassed sociodemographic information, type of poison, mode of poisoning, and clinical outcomes. Poison Severity Score (PSS) was employed to assess the severity. The most affected age group was preschool children (3–6 years), accounting for 41.5 % of cases, with males representing 52.8 %. Accidental poisoning constituted 83 % of cases, with household cleaning products (34 %) and petroleum products (18.9 %) being the most common toxic agents. Clinical outcomes revealed that 33 % of patients experienced morbidity, with electrolyte imbalances being the most prevalent complication. The overall cure rate was 94.3 %, while the mortality rate was 5.7 %. This study highlights the significance of parental education and preventive measures, especially in rural areas, to reduce the risk of pediatric poisoning. The PSS proved useful in guiding clinical care, supporting its further use in pediatric toxicology settings.
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使用中毒严重程度评分评估儿童急性中毒:埃及达米埃塔总医院的一项横断面研究
急性中毒是一个普遍存在的健康问题,尤其是在儿童中,因为他们天生好奇,喜欢探索。这项横断面研究旨在评估埃及达米埃塔综合医院儿童急性中毒的特征、原因、临床表现和结果。我们纳入了 106 名有明确急性中毒病史或临床症状的儿童患者(18 岁以下)。数据收集包括社会人口学信息、中毒类型、中毒方式和临床结果。中毒严重程度评分(PSS)用于评估中毒的严重程度。受影响最大的年龄组是学龄前儿童(3-6 岁),占 41.5%,其中男性占 52.8%。意外中毒占病例的 83%,最常见的毒物是家用清洁产品(34%)和石油产品(18.9%)。临床结果显示,33%的患者发病,电解质失衡是最常见的并发症。总体治愈率为 94.3%,死亡率为 5.7%。这项研究强调了家长教育和预防措施(尤其是在农村地区)对于降低小儿中毒风险的重要性。事实证明,PSS 在指导临床护理方面非常有用,支持在儿科毒物学领域进一步使用 PSS。
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来源期刊
Toxicology Reports
Toxicology Reports Environmental Science-Health, Toxicology and Mutagenesis
CiteScore
7.60
自引率
0.00%
发文量
228
审稿时长
11 weeks
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