Delineating cell types with transcriptional kinetics

IF 12 Q1 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS Nature computational science Pub Date : 2024-09-20 DOI:10.1038/s43588-024-00691-8
Yicheng Gao, Qi Liu
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Abstract

A recent study proposes an approach that integrates unspliced and spliced mRNA count data by leveraging shared biophysical states across cells, offering a more interpretable and consistent framework for determining cell clusters based on transcriptional kinetics.

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利用转录动力学划分细胞类型
最近的一项研究提出了一种方法,利用细胞间共享的生物物理状态整合未剪接和剪接的 mRNA 计数数据,为根据转录动力学确定细胞集群提供了一个更易于解释和一致的框架。
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