Early clinical outcomes and medical complications following long segment fusion for adult spinal deformity with and without three column osteotomy

Q1 Medicine World Neurosurgery: X Pub Date : 2024-09-25 DOI:10.1016/j.wnsx.2024.100415
Simon G. Ammanuel, Paul S. Page, Garret P. Greeneway, Darius Ansari, James A. Stadler
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Abstract

Background

Surgical treatment of adult spinal deformity (ASD) commonly involves long-segment fusion with or without three column osteotomies (3CO) to provide satisfactory correction of sagittal and coronal balance. While some clinical studies have implicated 3CO as a driver of high surgical complication rates, these prior investigations are limited by small sample size. Herein, we compare early outcomes and adverse events in patients undergoing long segment posterior spinal fusion for ASD with and without 3CO.

Methods

A multicenter administrative database was queried for patients undergoing elective posterior spinal fusion for ASD. Patients were stratified based upon long segment fusion with and without 3CO. Preoperative patient demographics, procedural characteristics, hospitalization events, and postoperative complication rates were evaluated. Student's t-test and Fisher's exact test were utilized where appropriate to compare differences between the two groups for continuous and categorical variables.

Results

340 cases met the inclusion criteria, of which 156 involved 3CO. Patients who required 3CO had a lower rate of preoperative diabetes (22.3 % vs 10.3 %, p = 0.003), higher rates of non-home discharge (26.2 % vs 57.1 %, p < 0.001), longer operation time (245.62 ± 9.45 vs. 434.40 ± 11.65, p < 0.001), and longer length of stay (4.17 ± 0.66 vs. 7.76 ± 0.83, p < 0.001). In terms of complications, 3CO patients had higher rates of deep surgical site infection (0 % vs 3.2 %, p = 0.02), reintubation (0 % vs 4.5 %, p = 0.004), inability to wean off ventilator (0 % vs 2.6 %, p = 0.04), and perioperative blood transfusion (20.1 % vs 76.3 %, p < 0.001).

Conclusions

In this retrospective analysis, posterior 3CO was frequently undertaken but associated with higher risk for postoperative adverse events following spinal deformity correction.
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采用或不采用三柱截骨术进行成人脊柱畸形长节段融合术后的早期临床疗效和医疗并发症
背景成人脊柱畸形(ASD)的手术治疗通常包括长节段融合,同时进行或不进行三柱截骨(3CO),以达到令人满意的矢状和冠状平衡矫正效果。虽然一些临床研究认为三柱截骨术是导致手术并发症发生率高的原因之一,但由于样本量较小,这些先前的研究受到了限制。在此,我们比较了因 ASD 而接受长节段脊柱后路融合术的患者有无 3CO 的早期结果和不良事件。根据有无 3CO 的长节段融合术对患者进行了分层。对术前患者的人口统计学特征、手术特征、住院事件和术后并发症发生率进行了评估。采用学生 t 检验和费雪精确检验来比较两组间连续变量和分类变量的差异。需要 3CO 的患者术前患糖尿病的比例较低(22.3 % vs 10.3 %,p = 0.003),非居家出院的比例较高(26.2 % vs 57.1 %,p < 0.001),手术时间较长(245.62 ± 9.45 vs 434.40 ± 11.65,p < 0.001),住院时间较长(4.17 ± 0.66 vs 7.76 ± 0.83,p < 0.001)。在并发症方面,3CO 患者的手术部位深部感染率(0 % vs 3.2 %,p = 0.02)、再次插管率(0 % vs 4.5 %,p = 0.004)、无法脱离呼吸机率(0 % vs 2.6 %,p = 0.04)和围手术期输血率(20.结论在这项回顾性分析中,脊柱畸形矫正术后经常使用后路 3CO,但术后发生不良事件的风险较高。
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来源期刊
World Neurosurgery: X
World Neurosurgery: X Medicine-Surgery
CiteScore
3.10
自引率
0.00%
发文量
23
审稿时长
44 days
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