A Linkable, Polycarbonate Gut Microbiome-Distal Tumor Chip Platform for Interrogating Cancer Promoting Mechanisms (Adv. Sci. 35/2024)

IF 14.3 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Advanced Science Pub Date : 2024-09-26 DOI:10.1002/advs.202470213
Danielle S.K. Brasino, Sean D. Speese, Kevin Schilling, Carolyn E. Schutt, Michelle C. Barton
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Abstract

Gut Microbiome-Distal Tumor Chip Platform

Polycarbonate organs-on-chip enhance control over growth conditions such as oxygen tension, enabling co-culture of gut epithelia and oxygen sensitive bacteria to model the gut microbiome. In article number 2309220 by Danielle S.K. Brasino and co-workers, a two-chip system is developed to study relationships between gut microbiota and distal tumors.

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一种可链接的聚碳酸酯肠道微生物组--分布式肿瘤芯片平台,用于研究癌症促进机制(科学进展 35/2024 号)
肠道微生物组-远端肿瘤芯片平台芯片上的聚碳酸酯器官增强了对氧张力等生长条件的控制,使肠道上皮细胞和氧敏感细菌的共培养成为肠道微生物组的模型。在 Danielle S.K. Brasino 及其合作者撰写的 2309220 号文章中,他们开发了一种双芯片系统,用于研究肠道微生物群与远端肿瘤之间的关系。
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来源期刊
Advanced Science
Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY
CiteScore
18.90
自引率
2.60%
发文量
1602
审稿时长
1.9 months
期刊介绍: Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.
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