Association of pain with falls and fractures among middle-aged Korean community-dwelling adults

Shaoli Yao, Xi-wen Chen
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Abstract

The relationship between pain and falls remains controversial. Therefore, this study explored the associations between pain and fall-related outcomes in 5,340 middle-aged (45–65 years) adults residing in the communities in Korea. Pain was defined as pain at any location, pain-related activity restriction (PAR), and persistent pain. The outcome measures included fall injuries, recurrent falls, injurious falls, and fall-related hip fractures. A multivariate logistic regression model was used to examine the relationship between pain and fall outcome. Among the study participants, 54.0% reported having experienced pain. During a follow-up period of up to 14 years, those who reported pain and PAR at baseline exhibited a positive association with the occurrence of fall injury (odds ratio [OR] 1.79, 95% confidence interval [CI] 1.27–2.53) and injurious falls (OR 1.72, 95% CI 1.20–2.48) but not with recurrent falls (OR 1.90, 95% CI 0.80–4.54). We also observed a positive association between persistent pain and the risk of fall injury (OR 1.41, 95% CI 1.13–1.91), whereas no consistent conclusions were drawn regarding the risk of recurrent falls and injurious falls. We also did not identify any correlation between pain and hip fractures resulting from falls. In conclusion, our findings of the positive correlations of pain and PAR at baseline with fall injuries and injurious falls but not recurrent falls during follow-up suggest that public health initiatives should prioritize pain screening, especially for participants reporting ankle and toe pain, and implement suitable interventions to mitigate the risk of falls and the associated adverse outcomes among middle-aged adults.
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韩国中年社区居民中疼痛与跌倒和骨折的关系
疼痛与跌倒之间的关系仍存在争议。因此,本研究以居住在韩国社区的 5340 名中年人(45-65 岁)为对象,探讨了疼痛与跌倒相关结果之间的关系。疼痛被定义为任何部位的疼痛、与疼痛相关的活动限制(PAR)和持续性疼痛。结果测量包括跌倒伤害、复发性跌倒、伤害性跌倒和与跌倒相关的髋部骨折。研究采用多变量逻辑回归模型来检验疼痛与跌倒结果之间的关系。在研究参与者中,54.0%的人表示曾经历过疼痛。在长达 14 年的随访期间,基线时报告疼痛和 PAR 的人与跌倒伤害的发生(几率比 [OR] 1.79,95% 置信区间 [CI] 1.27-2.53)和伤害性跌倒(OR 1.72,95% CI 1.20-2.48)呈正相关,但与复发性跌倒(OR 1.90,95% CI 0.80-4.54)无关。我们还观察到持续性疼痛与跌倒受伤风险之间存在正相关关系(OR 1.41,95% CI 1.13-1.91),而对于反复跌倒和伤害性跌倒的风险则没有得出一致的结论。我们也没有发现疼痛与跌倒导致的髋部骨折之间存在任何相关性。总之,我们的研究结果表明,基线疼痛和PAR与跌倒受伤和伤害性跌倒呈正相关,但与随访期间的复发性跌倒无关,这表明公共卫生活动应优先考虑疼痛筛查,尤其是对报告脚踝和脚趾疼痛的参与者,并实施适当的干预措施,以降低中年人跌倒的风险和相关的不良后果。
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