Zhantao Yang , Linlin Chen , Yuhang Zhao , Qianhui Chen , Wanjun Zhao , Linfei Li , Boxuan Zhang , Hua Xie , Xiangtao Kong , Chun-Hua Yang
{"title":"BCl3 catalyzed Z-selective intramolecular chlorocarbamoylation of alkynes/allenes†","authors":"Zhantao Yang , Linlin Chen , Yuhang Zhao , Qianhui Chen , Wanjun Zhao , Linfei Li , Boxuan Zhang , Hua Xie , Xiangtao Kong , Chun-Hua Yang","doi":"10.1039/d4qo01487a","DOIUrl":null,"url":null,"abstract":"<div><div>A metal-free stereoselective intramolecular chlorocarbamoylation of alkynes/allenes driven by BCl<sub>3</sub> was described, which provides a general and practical method for constructing versatile and chlorinated methylene lactams or tetrahydroisoquinolinones with (<em>Z</em>) geometry at the double bond, featuring a stereochemically defined tetrasubstituted chloroethene.</div></div>","PeriodicalId":94379,"journal":{"name":"Organic chemistry frontiers : an international journal of organic chemistry","volume":"11 23","pages":"Pages 6678-6683"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic chemistry frontiers : an international journal of organic chemistry","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S2052412924006764","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A metal-free stereoselective intramolecular chlorocarbamoylation of alkynes/allenes driven by BCl3 was described, which provides a general and practical method for constructing versatile and chlorinated methylene lactams or tetrahydroisoquinolinones with (Z) geometry at the double bond, featuring a stereochemically defined tetrasubstituted chloroethene.
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