Optimizing therapeutic efficacy of antifungal peptides via strategic terminal amino acid modification

IF 11.4 1区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES Journal of Advanced Research Pub Date : 2024-09-23 DOI:10.1016/j.jare.2024.09.017
Jing Song, Shanshan Zhang, Junya Xing, Licong Zhang, Jiajun Wang, Anshan Shan
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Abstract

Antifungal peptides (AFPs) have the potential to treat antifungal-resistant infections; however, their structure–function relationship remains unknown, hindering their rapid development. Therefore, it is imperative to investigate and clarify the structure–function relationships of AFPs.
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通过战略性末端氨基酸修饰优化抗真菌肽的疗效
抗真菌肽(AFPs)具有治疗抗真菌感染的潜力,但其结构与功能的关系仍然未知,阻碍了其快速发展。因此,研究和阐明抗真菌肽的结构与功能关系势在必行。
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来源期刊
Journal of Advanced Research
Journal of Advanced Research Multidisciplinary-Multidisciplinary
CiteScore
21.60
自引率
0.90%
发文量
280
审稿时长
12 weeks
期刊介绍: Journal of Advanced Research (J. Adv. Res.) is an applied/natural sciences, peer-reviewed journal that focuses on interdisciplinary research. The journal aims to contribute to applied research and knowledge worldwide through the publication of original and high-quality research articles in the fields of Medicine, Pharmaceutical Sciences, Dentistry, Physical Therapy, Veterinary Medicine, and Basic and Biological Sciences. The following abstracting and indexing services cover the Journal of Advanced Research: PubMed/Medline, Essential Science Indicators, Web of Science, Scopus, PubMed Central, PubMed, Science Citation Index Expanded, Directory of Open Access Journals (DOAJ), and INSPEC.
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