Disparities in the Representation of Sex, Race and Ethnicity in Tension-Type Headache Clinical Trials.

IF 2.9 4区 医学 Q2 CLINICAL NEUROLOGY Canadian Journal of Neurological Sciences Pub Date : 2024-09-26 DOI:10.1017/cjn.2024.300
Brendan Tao, Chia-Chen Tsai, Sina Marzoughi, Carmen Kalo, Jaden Lo, Arya Ebadi, Ana Marissa Lagman-Bartolome, Faisal Khosa
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Abstract

While tension-type headache (TTH) is the most common primary headache disorder, its effect according to sex, race and ethnicity remains unclear. We investigated disparities in sex, racial and ethnic representation in TTH clinical trials with comparison to global disease burdens. In this cross-sectional analysis, TTH clinical trials had female overrepresentation and racial and ethnic minority underrepresentation, which may affect understanding of the impact of TTH on different populations and personalized treatment development. Trial enrollment that is diverse and reflective of global disease burdens is crucial for improving study generalizability, understanding of diverse clinical presentations, and ensuring healthcare equity.

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紧张型头痛临床试验中性别、种族和民族代表性的差异。
紧张型头痛(TTH)是最常见的原发性头痛疾病,但其在性别、种族和民族方面的影响仍不明确。我们调查了 TTH 临床试验中性别、种族和民族代表性的差异,并与全球疾病负担进行了比较。在这项横断面分析中,TTH 临床试验中女性比例过高,而少数种族和族裔比例过低,这可能会影响人们对 TTH 对不同人群的影响以及个性化治疗开发的理解。试验入选者的多样性和对全球疾病负担的反映对于提高研究的普遍性、了解不同的临床表现和确保医疗公平至关重要。
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来源期刊
CiteScore
4.30
自引率
3.30%
发文量
330
审稿时长
4-8 weeks
期刊介绍: Canadian Neurological Sciences Federation The Canadian Journal of Neurological Sciences is the official publication of the four member societies of the Canadian Neurological Sciences Federation -- Canadian Neurological Society (CNS), Canadian Association of Child Neurology (CACN), Canadian Neurosurgical Society (CNSS), Canadian Society of Clinical Neurophysiologists (CSCN). The Journal is a widely circulated internationally recognized medical journal that publishes peer-reviewed articles. The Journal is published in January, March, May, July, September, and November in an online only format. The first Canadian Journal of Neurological Sciences (the Journal) was published in 1974 in Winnipeg. In 1981, the Journal became the official publication of the member societies of the CNSF.
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